7PGO

Crystal Structure of a Class D Carbapenemase_R250A

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (AAA, BBB, CCC, DDD)	Beta-lactamase	polymer	260	30168.0	4	UniProt (Q6XEC0) Pfam (PF00905)	Klebsiella pneumoniae
2	E, F, I, M (AAA, BBB, DDD)	1-BUTANOL	non-polymer		74.1	4	Chemie (1BO)
3	G, H, J, K, L (AAA, BBB)	BROMIDE ION	non-polymer		79.9	5	Chemie (BR)
4	N, O, P, Q (AAA, BBB, CCC, DDD)	water	water		18.0	901	Chemie (HOH)

Sequence modifications

AAA, BBB, CCC, DDD: 23 - 265 (UniProt: Q6XEC0)

PDB	External Database	Details
Met 6	-	initiating methionine
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 13	-	expression tag
Ala 14	-	expression tag
Gly 15	-	expression tag
Glu 16	-	expression tag
Asn 17	-	expression tag
Leu 18	-	expression tag
Tyr 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag
Gly 22	-	expression tag
Ala 250	Arg 250	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	120672.1
Non-Polymers*	Number of molecules	9
	Total formula weight	696.0
All*	Total formula weight	121368.1

*Water molecules are not included.