7PGN
HHP-C in complex with glycosaminoglycan mimic SOS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hedgehog-interacting protein | polymer | 470 | 52504.5 | 2 | UniProt (Q96QV1) Pfam (PF07995) Pfam (PF07974) | Homo sapiens (Human) | HHIP,HIP |
| 2 | C, D, E, F (E, F, G, H) | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose | branched | 982.8 | 4 | In PDB BIRD (PRD_900013) | |||
| 3 | G, I (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B: 213 - 670 (UniProt: Q96QV1)
| PDB | External Database | Details |
|---|---|---|
| Glu 210 | - | expression tag |
| Thr 211 | - | expression tag |
| Gly 212 | - | expression tag |
| Gly 671 | - | expression tag |
| Thr 672 | - | expression tag |
| Lys 673 | - | expression tag |
| His 674 | - | expression tag |
| His 675 | - | expression tag |
| His 676 | - | expression tag |
| His 677 | - | expression tag |
| His 678 | - | expression tag |
| His 679 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 105009.0 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3931.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 172.3 | |
| All* | Total formula weight | 109112.5 |
