7PG3
Low resolution Cryo-EM structure of the full-length insulin receptor bound to 3 insulin, conf 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform Short of Insulin receptor | polymer | 1382 | 156697.6 | 2 | UniProt (P06213) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF17870) Pfam (PF07714) | Homo sapiens (Human) | IR |
| 2 | C, E, G (C, E, I) | Insulin | polymer | 21 | 2383.7 | 3 | UniProt (P01308) | Homo sapiens (Human) | |
| 3 | D, F, H (D, F, J) | Insulin | polymer | 30 | 3434.0 | 3 | UniProt (P01308) Pfam (PF00049) | Homo sapiens (Human) |
Sequence modifications
A, B: -26 - 1343 (UniProt: P06213)
| PDB | External Database | Details |
|---|---|---|
| Glu 1344 | - | expression tag |
| Asp 1345 | - | expression tag |
| Gln 1346 | - | expression tag |
| Val 1347 | - | expression tag |
| Asp 1348 | - | expression tag |
| Pro 1349 | - | expression tag |
| Arg 1350 | - | expression tag |
| Leu 1351 | - | expression tag |
| Ile 1352 | - | expression tag |
| Asp 1353 | - | expression tag |
| Gly 1354 | - | expression tag |
| Lys 1355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 330848.1 | |
| All* | Total formula weight | 330848.1 |
