7PEI

Crystal Structure of a Class D carbapenemase_E185A/R186A/R206A

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB	Beta-lactamase	polymer	260	30023.9	2	UniProt (A0A482LRD5) Pfam (PF00905) In PDB	Klebsiella pneumoniae
2	AAA, BBB	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
3	AAA, BBB	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4		water	water		18.0	257	Chemie (HOH)

Sequence modifications

AAA, BBB: 23 - 265 (UniProt: A0A482LRD5)

PDB	External Database	Details
Met 6	-	initiating methionine
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 13	-	expression tag
Ala 14	-	expression tag
Gly 15	-	expression tag
Glu 16	-	expression tag
Asn 17	-	expression tag
Leu 18	-	expression tag
Tyr 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag
Gly 22	-	expression tag
Ala 185	Glu 175	engineered mutation
Ala 186	Arg 176	engineered mutation
Ala 206	Arg 196	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60047.7
Non-Polymers*	Number of molecules	9
	Total formula weight	848.7
All*	Total formula weight	60896.4

*Water molecules are not included.