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focus refinement of soluble domain of adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Adenylate cyclase 9	polymer	1354	151142.9	1	UniProt (E1BM79) Pfam (PF00211) In PDB	Bos taurus (cattle)
2	B	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	polymer	405	47003.8	1	UniProt (P04896) Pfam (PF00503) In PDB	Bos taurus (Bovine)	Adenylate cyclase-stimulating G alpha protein
3	B	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE	non-polymer		539.2	1	Chemie (GSP)
4	B	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

B: 1 - 394 (UniProt: P04896)

PDB	External Database	Details
Gly 65	-	insertion
Asn 65	Gln 78	conflict
Lys 65	Arg 81	conflict
Gly 395	-	expression tag
Gly 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	198146.7
Non-Polymers*	Number of molecules	2
	Total formula weight	563.6
All*	Total formula weight	198710.2

*Water molecules are not included.