7PD1
Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thiazole biosynthesis protein ThiH | polymer | 377 | 43035.1 | 2 | UniProt (A1HPQ5) Pfam (PF04055) Pfam (PF06968) | Thermosinus carboxydivorans Nor1 | 2-iminoacetate synthase ThiH |
| 2 | C, Q (A, B) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
| 3 | D, R (A, B) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 2 | Chemie (5AD) | |||
| 4 | E, S (A, B) | METHIONINE | non-polymer | 149.2 | 2 | Chemie (MET) | |||
| 5 | F, T (A, B) | TYROSINE | non-polymer | 181.2 | 2 | Chemie (TYR) | |||
| 6 | G, H, I, V, W (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | J (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 8 | AA, BA, K, L, M... (B, A) | BROMIDE ION | non-polymer | 79.9 | 11 | Chemie (BR) | |||
| 9 | U (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 10 | CA, DA (A, B) | water | water | 18.0 | 962 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 367 (UniProt: A1HPQ5)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Trp -8 | - | expression tag |
| Ser -7 | - | expression tag |
| His -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86070.1 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3357.0 | |
| All* | Total formula weight | 89427.2 |
