7PD1
Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thiazole biosynthesis protein ThiH | polymer | 377 | 43035.1 | 2 | UniProt (A1HPQ5) Pfam (PF04055) Pfam (PF06968) | Thermosinus carboxydivorans Nor1 | 2-iminoacetate synthase ThiH |
| 2 | C, Q (A, B) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
| 3 | D, R (A, B) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 2 | Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (23638944) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (71678) PubChem (23615209) PubChem (40467849) PubChem (57115448) PubChem (439182) PubChem (59731278) PubChem (449044) PubChem (1277776) PubChem (90321697) PubChem (676784) PubChem (6541038) PubChem (6398669) PubChem (6928544) PubChem (121275112) PubChem (124363198) PubChem (12827542) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934) | |||
| 4 | E, S (A, B) | METHIONINE | non-polymer | 149.2 | 2 | Chemie (MET) PubChem (876) PubChem (6137) PubChem (84815) | |||
| 5 | F, T (A, B) | TYROSINE | non-polymer | 181.2 | 2 | Chemie (TYR) PubChem (1153) PubChem (6057) PubChem (71098) | |||
| 6 | G, H, I, V, W (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | J (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 8 | AA, BA, K, L, M... (B, A) | BROMIDE ION | non-polymer | 79.9 | 11 | Chemie (BR) PubChem (259) | |||
| 9 | U (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 10 | CA, DA (A, B) | water | water | 18.0 | 962 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 367 (UniProt: A1HPQ5)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Trp -8 | - | expression tag |
| Ser -7 | - | expression tag |
| His -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86070.1 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 3357.0 | |
| All* | Total formula weight | 89427.2 |
