7PCU
Crystal structure of YTHDF1 YTH domain in complex with ebselen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | YTH domain-containing family protein 1 | polymer | 200 | 23148.2 | 2 | UniProt (Q9BYJ9) Pfam (PF04146) | Homo sapiens (Human) | DF1,Dermatomyositis associated with cancer putative autoantigen 1,DACA-1 |
| 2 | C, D (A, B) | N-phenyl-2-selanylbenzamide | non-polymer | 276.2 | 2 | Chemie (9JT) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B: 361 - 559 (UniProt: Q9BYJ9)
| PDB | External Database | Details |
|---|---|---|
| Gly 360 | - | expression tag |
| Ala 544 | Glu 544 | engineered mutation |
| Val 545 | Glu 545 | engineered mutation |
| Val 546 | Glu 546 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46296.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 552.4 | |
| All* | Total formula weight | 46848.7 |
