7PCU
Crystal structure of YTHDF1 YTH domain in complex with ebselen
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | YTH domain-containing family protein 1 | polymer | 200 | 23148.2 | 2 | UniProt (Q9BYJ9) Pfam (PF04146) In PDB | Homo sapiens (Human) | DF1,Dermatomyositis associated with cancer putative autoantigen 1,DACA-1 |
2 | A, B | N-phenyl-2-selanylbenzamide | non-polymer | 276.2 | 2 | Chemie (9JT) | |||
3 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B: 361 - 559 (UniProt: Q9BYJ9)
PDB | External Database | Details |
---|---|---|
Gly 360 | - | expression tag |
Ala 544 | Glu 544 | engineered mutation |
Val 545 | Glu 545 | engineered mutation |
Val 546 | Glu 546 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 46296.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 552.4 | |
All* | Total formula weight | 46848.7 |