7PC7
The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Gamma-1-syntrophin,Annexin A2 | polymer | 414 | 46770.4 | 2 | UniProt (Q9NSN8) UniProt (P07355) Pfam (PF00595) Pfam (PF00191) In PDB | Homo sapiens (Human) | G1SYN,Syntrophin-4,SYN4,Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36 |
| 2 | E, F | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | polymer | 10 | 1241.3 | 2 | UniProt (P60484) In PDB | Homo sapiens | Mutated in multiple advanced cancers 1,Phosphatase and tensin homolog |
| 3 | A, B | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 405 | Chemie (HOH) |
Sequence modifications
A, B: 54 - 140 (UniProt: Q9NSN8)
A, B: 140 - 461 (UniProt: P07355)
| PDB | External Database | Details |
|---|---|---|
| Gly 49 | - | expression tag |
| Ser 50 | - | expression tag |
| His 51 | - | expression tag |
| Met 52 | - | expression tag |
| Gly 53 | - | expression tag |
| Gly 140 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 188 | Ala 66 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96023.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 849.3 | |
| All* | Total formula weight | 96872.7 |
