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7PBE

Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, FMHC class I antigenpolymer27631951.32UniProt (A0A5B8RNS7)
Pfam (PF00129)
Pfam (PF07654)
UniProt (by SIFTS) (A0A140T913)
In PDB
Homo sapiens (Human)
2B, GBeta-2-microglobulinpolymer10011879.42UniProt (P61769)
Pfam (PF07654)
In PDB
Homo sapiens (Human)
3C, HSpike protein S1polymer91151.42UniProt (P0DTC2)
In PDB
Severe acute respiratory syndrome coronavirus 2
4D, IHuman T-cell Receptor YLQ36, alpha chainpolymer20322749.12Homo sapiens (Human)
5E, JHuman T-cell Receptor YLQ36, beta chainpolymer24327690.62Homo sapiens (Human)
6A, FDI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
7A, B, E, F, ISULFATE IONnon-polymer96.15Chemie (SO4)
Sequence modifications
B, G: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight190843.5
Non-Polymers*Number of molecules7
Total formula weight692.6
All*Total formula weight191536.1
*Water molecules are not included.

221716

PDB entries from 2024-06-26

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