7PAY
Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium and GGsPP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dehydrodolichyl diphosphate synthase complex subunit DHDDS | polymer | 340 | 39202.0 | 1 | UniProt (Q86SQ9) Pfam (PF01255) In PDB | Homo sapiens (Human) | Cis-isoprenyltransferase,Cis-IPTase,Cis-prenyltransferase subunit hCIT,Epididymis tissue protein Li 189m |
2 | B | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | polymer | 219 | 24211.6 | 1 | UniProt (Q96E22) Pfam (PF01255) In PDB | Homo sapiens (Human) | Cis-prenyltransferase subunit NgBR,Nogo-B receptor,NgBR,Nuclear undecaprenyl pyrophosphate synthase 1 homolog |
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | phosphonooxy-[(10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanyl-phosphinic acid | non-polymer | 466.5 | 1 | Chemie (GGS) | |||
6 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A: 1 - 333 (UniProt: Q86SQ9)
B: 73 - 293 (UniProt: Q96E22)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Gly 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 66 | - | expression tag |
Ser 67 | - | expression tag |
Gly 68 | - | expression tag |
Ser 69 | - | expression tag |
Gly 70 | - | expression tag |
Ser 71 | - | expression tag |
Gly 72 | - | expression tag |
- | Tyr 167 | deletion |
- | Ser 168 | deletion |
- | Pro 169 | deletion |
- | Glu 170 | deletion |
- | Phe 171 | deletion |
- | Ala 172 | deletion |
- | Asn 173 | deletion |
- | Ser 174 | deletion |
- | Asn 175 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63413.6 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 586.9 | |
All* | Total formula weight | 64000.4 |