7PAC

The crystal structure of PDE6D in the apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	polymer	166	19353.0	1	UniProt (O43924) Pfam (PF05351)	Homo sapiens (Human)	GMP-PDE delta,Protein p17
2	B (B)	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
3	C (B)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
4	D (B)	water	water		18.0	102	Chemie (HOH)

Sequence modifications

B: 2 - 150 (UniProt: O43924)

PDB	External Database	Details
Met -15	-	initiating methionine
Gly -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Glu -4	-	expression tag
Asn -3	-	expression tag
Leu -2	-	expression tag
Tyr -1	-	expression tag
Phe 0	-	expression tag
Gln 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19353.0
Non-Polymers*	Number of molecules	2
	Total formula weight	297.0
All*	Total formula weight	19650.0

*Water molecules are not included.