7P6Q

ROCK2 IN COMPLEX WITH COMPOUND 21

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Rho-associated protein kinase 2	polymer	399	45700.9	4	UniProt (O75116) Pfam (PF00069)	Homo sapiens (Human)	Rho kinase 2,Rho-associated,coiled-coil-containing protein kinase 2,coiled-coil-containing protein kinase II,ROCK-II,p164 ROCK-2
2	E, F, G, H (A, B, C, D)	4-(3-fluoranylpyridin-4-yl)-~{N}-[(1~{R})-1-(3-methoxyphenyl)ethyl]piperazine-1-carboxamide	non-polymer		358.4	4	Chemie (5YO)
3	I, J, K, L (A, B, C, D)	water	water		18.0	25	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	182803.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1433.6
All*	Total formula weight	184237.3

*Water molecules are not included.