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7P6O

ROCK2 IN COMPLEX WITH COMPOUND 8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Rho-associated protein kinase 2polymer39945700.98UniProt (O75116)
Pfam (PF00069)
Homo sapiens (Human)Rho kinase 2,Rho-associated,coiled-coil-containing protein kinase 2,coiled-coil-containing protein kinase II,ROCK-II,p164 ROCK-2
2I, K, L, M, O...
(A, B, C, D, E...)
6-(2-fluoranylpyridin-4-yl)-~{N}-[(1~{R})-1-(3-methoxyphenyl)ethyl]pyridine-3-carboxamidenon-polymer351.48Chemie (5YK)
3J, N, S
(A, D, H)
GLYCEROLnon-polymer92.13Chemie (GOL)
4AA, T, U, V, W...
(H, A, B, C, D...)
waterwater18.077Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight365607.3
Non-Polymers*Number of molecules11
Total formula weight3087.3
All*Total formula weight368694.6
*Water molecules are not included.

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PDB entries from 2026-03-25

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