7P4Q
Structure of the quinolinate synthase S124A variant complexed with citrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Quinolinate synthase A | polymer | 305 | 34640.6 | 1 | UniProt (Q9X1X7) Pfam (PF02445) In PDB | Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) | |
| 2 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 3 | A | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 4 | A | FE3-S4 CLUSTER | non-polymer | 295.8 | 1 | Chemie (F3S) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: Q9X1X7)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 124 | Ser 124 | engineered mutation |
| Arg 219 | Lys 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34640.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1460.0 | |
| All* | Total formula weight | 36100.6 |
