7P4O
Crystal structure of Autotaxin and 9(R)-delta6a,10a-THC
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | polymer | 827 | 95037.7 | 1 | UniProt (Q64610) Pfam (PF01033) Pfam (PF01663) Pfam (PF01223) In PDB | Rattus norvegicus (Norway rat) | E-NPP 2,Autotaxin,Extracellular lysophospholipase D,LysoPLD |
2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | A | 7alpha-hydroxycholesterol | non-polymer | 402.7 | 1 | Chemie (5JK) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | A | (9~{R},10~{a}~{S})-6,6,9-trimethyl-3-pentyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol | non-polymer | 316.5 | 1 | Chemie (5K9) | |||
6 | A | THIOCYANATE ION | non-polymer | 58.1 | 2 | Chemie (SCN) | |||
7 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
8 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | A | IODIDE ION | non-polymer | 126.9 | 12 | Chemie (IOD) | |||
10 | water | water | 18.0 | 461 | Chemie (HOH) |
Sequence modifications
A: 36 - 862 (UniProt: Q64610)
PDB | External Database | Details |
---|---|---|
Ala 410 | Asn 410 | engineered mutation |
Phe 581 | Leu 581 | engineered mutation |
Thr 591 | Arg 591 | engineered mutation |
Ala 806 | Asn 806 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 95037.7 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 2713.2 | |
All* | Total formula weight | 98175.3 |