7P4K
Soluble epoxide hydrolase in complex with FL217
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bifunctional epoxide hydrolase 2 | polymer | 346 | 39648.5 | 2 | UniProt (P34913) Pfam (PF00561) In PDB | Homo sapiens (Human) | |
2 | A, B | ~{N}-[[4-(cyclopropylsulfonylamino)-2-(trifluoromethyl)phenyl]methyl]-1-[(3-fluorophenyl)methyl]indole-5-carboxamide | non-polymer | 545.5 | 2 | Chemie (5IV) | |||
3 | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A, B: 222 - 555 (UniProt: P34913)
PDB | External Database | Details |
---|---|---|
Met 219 | - | initiating methionine |
Ala 220 | - | expression tag |
Ser 221 | - | expression tag |
Leu 556 | - | expression tag |
Leu 557 | - | expression tag |
Glu 558 | - | expression tag |
His 559 | - | expression tag |
His 560 | - | expression tag |
His 561 | - | expression tag |
His 562 | - | expression tag |
His 563 | - | expression tag |
His 564 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 79297.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1091.1 | |
All* | Total formula weight | 80388.2 |