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7P3J

EED in complex with compound 4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Polycomb protein EEDpolymer36642299.22UniProt (O75530)
Pfam (PF00400)
Homo sapiens (Human)hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1
2C, D, E
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
3F
(A)
N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-aminenon-polymer421.51Chemie (L9W)
4G
(B)
8-[6-[(dimethylamino)methyl]-2-methyl-pyridin-3-yl]-5-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2H-pyrido[3,4-d]pyridazin-1-onenon-polymer460.51Chemie (54N)
5H, I
(A, B)
waterwater18.0472Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight84598.4
Non-Polymers*Number of molecules5
Total formula weight954.9
All*Total formula weight85553.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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