7P1H
Structure of the V. vulnificus ExoY-G-actin-profilin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltose/maltodextrin-binding periplasmic protein,RTX-toxin | polymer | 827 | 91467.5 | 1 | UniProt (P0AEX9) UniProt (A0A0F6NGV0) Pfam (PF01547) Pfam (PF03497) UniProt (by SIFTS) (A0A023NA98) | Escherichia coli (strain K12) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP |
| 2 | B (B) | Actin, cytoplasmic 1 | polymer | 372 | 41402.2 | 1 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (Human) | Beta-actin |
| 3 | C (P) | Profilin-1 | polymer | 140 | 15071.2 | 1 | UniProt (P07737) Pfam (PF00235) | Homo sapiens (Human) | Epididymis tissue protein Li 184a,Profilin I |
| 4 | D (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E (B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A: -376 - -11 (UniProt: P0AEX9)
A: 0 - 429 (UniProt: A0A0F6NGV0)
B: 4 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Met -397 | - | initiating methionine |
| Gly -396 | - | expression tag |
| Ser -395 | - | expression tag |
| Ser -394 | - | expression tag |
| His -393 | - | expression tag |
| His -392 | - | expression tag |
| His -391 | - | expression tag |
| His -390 | - | expression tag |
| His -389 | - | expression tag |
| His -388 | - | expression tag |
| Ser -387 | - | expression tag |
| Ser -386 | - | expression tag |
| Gly -385 | - | expression tag |
| Leu -384 | - | expression tag |
| Val -383 | - | expression tag |
| Pro -382 | - | expression tag |
| Arg -381 | - | expression tag |
| Gly -380 | - | expression tag |
| Ser -379 | - | expression tag |
| His -378 | - | expression tag |
| Met -377 | - | expression tag |
| Val -65 | Ala 338 | conflict |
| Asn -10 | - | linker |
| Ser -9 | - | linker |
| Gly -8 | - | linker |
| Ser -7 | - | linker |
| Ser -6 | - | linker |
| Gly -5 | - | linker |
| Ser -4 | - | linker |
| Ser -3 | - | linker |
| Val -2 | - | linker |
| Glu -1 | - | linker |
B: 4 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 147941.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.3 | |
| All* | Total formula weight | 148488.3 |
