7P19
Crystal structure of SARS-CoV-2 RBD Q498Y complexed with human ACE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Processed angiotensin-converting enzyme 2 | polymer | 599 | 69307.8 | 2 | UniProt (Q9BYF1) Pfam (PF01401) | Homo sapiens (Human) | |
| 2 | B, D (E, C) | Spike protein S1 | polymer | 210 | 23570.6 | 2 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 3 | E, G, I, K, M... (A, E, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 4 | F, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, N (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | J (E) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) |
Sequence modifications
A, B: 19 - 615 (UniProt: Q9BYF1)
E, C: 334 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Pro 18 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 332 | - | expression tag |
| Pro 333 | - | expression tag |
| Tyr 498 | Gln 498 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 185756.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1838.9 | |
| All* | Total formula weight | 187595.6 |
