7P0Y
Crystal Structure of mtbMGL K74A (Substrate Analog Complex)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Monoacylglycerol lipase | polymer | 284 | 30643.9 | 2 | UniProt (O07427) Pfam (PF12146) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | MGL |
| 2 | C, D (A, B) | 1-[butyl(fluoranyl)phosphoryl]oxyhexadecane | non-polymer | 364.5 | 2 | Chemie (4E0) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 279 (UniProt: O07427)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 74 | Lys 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61287.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 729.0 | |
| All* | Total formula weight | 62016.8 |
