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7P0U

ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, B, D, F)
Apoptosis inhibitorpolymer14816160.34UniProt (A0A0R8HV90)Orf virus (ORFV)
2B, D, F, H
(U, C, E, G)
Activator of apoptosis harakiripolymer262973.44UniProt (O00198)Homo sapiensBH3-interacting domain-containing protein 3,Neuronal death protein DP5
3I, J, M, N, P
(A, B, F)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
4K, L, O
(A, C)
GLYCEROLnon-polymer92.13Chemie (GOL)
PubChem (753)
5Q, R, S, T, U...
(A, U, B, C, D...)
waterwater18.070Chemie (HOH)
Sequence modifications
A, B, D, F: 1 - 143 (UniProt: A0A0R8HV90)
PDBExternal DatabaseDetails
Gly -4-expression tag
Pro -3-expression tag
Leu -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight76534.7
Non-Polymers*Number of molecules8
Total formula weight586.6
All*Total formula weight77121.3
*Water molecules are not included.

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PDB entries from 2026-03-25

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