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7OZF

FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 19.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAA, BBBFibroblast growth factor receptor 1polymer30935135.32UniProt (P11362)
Pfam (PF07714)
In PDB
Homo sapiens (Human)FGFR-1,Basic fibroblast growth factor receptor 1,bFGF-R-1,Fms-like tyrosine kinase 2,FLT-2,N-sam,Proto-oncogene c-Fgr
2AAA, BBBN-[6-(3-ethoxyphenyl)-1H-indazol-3-yl]benzamidenon-polymer357.42Chemie (466)
3AAASULFATE IONnon-polymer96.11Chemie (SO4)
4AAA, BBB1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
5AAA, BBBCHLORIDE IONnon-polymer35.52Chemie (CL)
6waterwater18.0183Chemie (HOH)
Sequence modifications
AAA, BBB: 458 - 765 (UniProt: P11362)
PDBExternal DatabaseDetails
Gly 457-expression tag
Ala 488Cys 488conflict
Ser 584Cys 584conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70270.7
Non-Polymers*Number of molecules9
Total formula weight1130.1
All*Total formula weight71400.7
*Water molecules are not included.

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PDB entries from 2024-07-10

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