7OYG

Dimeric form of SARS-CoV-2 RNA-dependent RNA polymerase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, F (A, D)	SARS-CoV-2 RNA-dependent RNA polymerase (nsp12)	polymer	935	107053.2	2	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
2	B, G (B, E)	SARS-CoV-2 nsp8	polymer	201	22175.3	2	UniProt (P0DTD1) Pfam (PF08717)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
3	C, H (C, F)	SARS-CoV-2 nsp7	polymer	86	9521.1	2	UniProt (P0DTD1) Pfam (PF08716)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein
4	D, I (P, G)	RNA (5'-R(P*CP*UP*AP*CP*GP*CP*AP*GP*UP*G)-3')	polymer	15	4807.9	2		Severe acute respiratory syndrome coronavirus 2
5	E, J (T, H)	RNA (5'-R(P*UP*GP*CP*AP*CP*UP*GP*CP*GP*UP*AP*G)-3')	polymer	57	18138.7	2		Severe acute respiratory syndrome coronavirus 2
6	K, L, M, N (A, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

A, D: 1 - 932 (UniProt: P0DTD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

B, E: 1 - 198 (UniProt: P0DTD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

C, F: 1 - 83 (UniProt: P0DTD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	323392.3
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	323654.0

*Water molecules are not included.