7OY5
Crystal structure of GSK3Beta in complex with ARN25068
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 351 | 39930.9 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | C, H (A, B) | ~{N}4-(3-cyclopropyl-1~{H}-pyrazol-5-yl)-~{N}2-(phenylmethyl)thieno[3,2-d]pyrimidine-2,4-diamine | non-polymer | 362.5 | 2 | Chemie (39I) | |||
| 3 | D, E, F, G, I... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79861.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 937.6 | |
| All* | Total formula weight | 80799.5 |
