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7OVO

Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Queuine tRNA-ribosyltransferase accessory subunit 2polymer41946710.51UniProt (B8ZXI1)
Pfam (PF01702)
Mus musculus (Mouse)Queuine tRNA-ribosyltransferase domain-containing protein 1
2B
(C)
Queuine tRNA-ribosyltransferase catalytic subunit 1polymer39543429.01UniProt (Q9JMA2)
Pfam (PF01702)
Mus musculus (Mouse)Guanine insertion enzyme,tRNA-guanine transglycosylase
3C, H
(A, C)
ZINC IONnon-polymer65.42Chemie (ZN)
4D, E, I, J, K...
(A, C)
SULFATE IONnon-polymer96.17Chemie (SO4)
5F
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
6G
(C)
2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-onenon-polymer277.31Chemie (QEI)
7N, O
(A, C)
waterwater18.0239Chemie (HOH)
Sequence modifications
A: 2 - 415 (UniProt: B8ZXI1)
PDBExternal DatabaseDetails
Gly 0-cloning artifact
Pro 1-cloning artifact
Asp 416-expression tag
Asn 417-expression tag
Asn 418-expression tag
C: 11 - 403 (UniProt: Q9JMA2)
PDBExternal DatabaseDetails
Gly 9-cloning artifact
Pro 10-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight90139.4
Non-Polymers*Number of molecules11
Total formula weight1158.7
All*Total formula weight91298.1
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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