7OUT
HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND INHIBITOR RMC-264
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, A | Reverse transcriptase/ribonuclease H | polymer | 556 | 64022.4 | 2 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) | Exoribonuclease H,p66 RT |
2 | D, B | Reverse transcriptase/ribonuclease H | polymer | 428 | 50039.5 | 2 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) | Exoribonuclease H,p51 RT |
3 | E, T | DNA (5'-D(P*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3') | polymer | 27 | 8383.4 | 2 | Human immunodeficiency virus type 1 BH10 | ||
4 | F, P | DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3') | polymer | 21 | 6474.3 | 2 | Homo sapiens | ||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
6 | A | (S)-2-(3-(6-amino-9H-purin-9-yl)propoxy)-3-phosphonopropanoic acid | non-polymer | 345.2 | 1 | Chemie (1KK) | |||
7 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
C, A: 1 - 554 (UniProt: P03366)
D, B: 1 - 428 (UniProt: P03366)
PDB | External Database | Details |
---|---|---|
Met -1 | - | initiating methionine |
Val 0 | - | expression tag |
Cys 258 | Gln 857 | conflict |
Ser 280 | Cys 879 | conflict |
Asn 498 | Asp 1097 | conflict |
PDB | External Database | Details |
---|---|---|
Ser 280 | Cys 879 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 257839.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 369.6 | |
All* | Total formula weight | 258208.7 |