7OUK
BDM88855 inhibitor bound to the transmembrane domain of AcrB
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Multidrug efflux pump subunit AcrB | polymer | 1057 | 114736.3 | 3 | UniProt (P31224) Pfam (PF00873) In PDB | Escherichia coli | AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B |
2 | D, E | DARPIN | polymer | 169 | 18317.6 | 2 | synthetic construct | ||
3 | B, A, C | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 8 | Chemie (LMT) | |||
4 | A, B | 3-chloranyl-2-piperazin-1-yl-quinoline | non-polymer | 247.7 | 2 | Chemie (1K8) | |||
5 | B, A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
6 | A, C | N-OCTANE | non-polymer | 114.2 | 3 | Chemie (OCT) | |||
7 | A, C | TETRADECANE | non-polymer | 198.4 | 3 | Chemie (C14) | |||
8 | B, A, C | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
9 | B | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
10 | B | (2S)-3-hydroxypropane-1,2-diyl didecanoate | non-polymer | 400.6 | 1 | Chemie (DDR) | |||
11 | B | DECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 201.3 | 1 | Chemie (DDQ) | |||
12 | B, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
13 | C | (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate | non-polymer | 453.6 | 2 | Chemie (LPX) | |||
14 | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 1049 (UniProt: P31224)
PDB | External Database | Details |
---|---|---|
Leu 1050 | - | expression tag |
Glu 1051 | - | expression tag |
His 1052 | - | expression tag |
His 1053 | - | expression tag |
His 1054 | - | expression tag |
His 1055 | - | expression tag |
His 1056 | - | expression tag |
His 1057 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 380844.0 | |
Non-Polymers* | Number of molecules | 44 |
Total formula weight | 8879.2 | |
All* | Total formula weight | 389723.2 |