7OTW

DNA-PKcs in complex with AZD7648

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA-dependent protein kinase catalytic subunit,DNA-PKcs	polymer	4148	471375.4	1	UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) In PDB	Homo sapiens (Human)	DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460
2	A	7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one	non-polymer		380.4	1	Chemie (MBW)

Sequence modifications

A: 1 - 4128 (UniProt: P78527)
A: 6001 - 6020 (PDB: 7OTW)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	471375.4
Non-Polymers*	Number of molecules	1
	Total formula weight	380.4
All*	Total formula weight	471755.8

*Water molecules are not included.