7OTS
Crystal structure of human Monoacylglycerol Lipase ABHD6 in complex with oleic acid and octyl glucoside
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Monoacylglycerol lipase ABHD6 | polymer | 297 | 33748.1 | 2 | UniProt (Q9BV23) Pfam (PF00561) | Homo sapiens (Human) | 2-arachidonoylglycerol hydrolase,Abhydrolase domain-containing protein 6 |
| 2 | C (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 3 | D, G (A, B) | OLEIC ACID | non-polymer | 282.5 | 2 | Chemie (OLA) | |||
| 4 | E, F, K (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | H, I, J (B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 337 (UniProt: Q9BV23)
| PDB | External Database | Details |
|---|---|---|
| Ser 41 | - | expression tag |
| Met 42 | - | expression tag |
| Ala 148 | Ser 148 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67496.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1421.8 | |
| All* | Total formula weight | 68918.1 |
