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7OT0

Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 4h

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Bifunctional glutamate/proline--tRNA ligasepolymer51258087.42UniProt (P07814)
Pfam (PF00587)
Pfam (PF03129)
Pfam (PF09180)
Homo sapiens (Human)Bifunctional aminoacyl-tRNA synthetase,Cell proliferation-inducing gene 32 protein,Glutamatyl-prolyl-tRNA synthetase
2C, H
(A, B)
PROLINEnon-polymer115.12Chemie (PRO)
3D, I
(A, B)
3-[(2-chlorophenyl)methylamino]pyrazine-2-carboxamidenon-polymer262.72Chemie (0YI)
4E, J
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
5F, G
(A)
STRONTIUM IONnon-polymer87.62Chemie (SR)
6K, L
(A, B)
waterwater18.0100Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight116174.8
Non-Polymers*Number of molecules8
Total formula weight1061.7
All*Total formula weight117236.5
*Water molecules are not included.

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PDB entries from 2025-07-23

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