7ORL
La Crosse virus polymerase at transcription initiation stage
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | P | RNA (5'-D(*(GTG))-R(P*AP*AP*UP*AP*CP*UP*AP*UP*AP*GP*UP*A)-3') | polymer | 15 | 4785.9 | 1 | La Crosse virus | ||
| 2 | A | RNA-directed RNA polymerase L | polymer | 2276 | 264751.1 | 1 | UniProt (A5HC98) Pfam (PF15518) Pfam (PF04196) Pfam (PF21561) In PDB | La Crosse virus | Protein L,Large structural protein,Replicase,Transcriptase |
| 3 | H | RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3') | polymer | 17 | 5466.3 | 1 | La Crosse virus | ||
| 4 | T | RNA (5'-R(P*CP*UP*UP*GP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3') | polymer | 25 | 7882.7 | 1 | La Crosse virus | ||
| 5 | P | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE | non-polymer | 803.4 | 1 | Chemie (GTG) | |||
| 6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | A | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 8 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 1 - 2263 (UniProt: A5HC98)
| PDB | External Database | Details |
|---|---|---|
| Lys 34 | His 34 | engineered mutation |
| Ser 1031 | - | insertion |
| Gly 1031 | - | insertion |
| Trp 1031 | - | insertion |
| Ser 1031 | - | insertion |
| His 1031 | - | insertion |
| Pro 1031 | - | insertion |
| Gln 1031 | - | insertion |
| Phe 1031 | - | insertion |
| Glu 1031 | - | insertion |
| Lys 1031 | - | insertion |
| Gly 1031 | - | insertion |
| Ser 1031 | - | insertion |
| Gly 1031 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 282886.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1069.1 | |
| All* | Total formula weight | 283955.1 |
