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7ORL

La Crosse virus polymerase at transcription initiation stage

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(P)
RNA (5'-D(*(GTG))-R(P*AP*AP*UP*AP*CP*UP*AP*UP*AP*GP*UP*A)-3')polymer154785.91La Crosse virus
2B
(A)
RNA-directed RNA polymerase Lpolymer2276264751.11UniProt (A5HC98)La Crosse virusProtein L,Large structural protein,Replicase,Transcriptase
3C
(H)
RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3')polymer175466.31La Crosse virus
4D
(T)
RNA (5'-R(P*CP*UP*UP*GP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3')polymer257882.71La Crosse virus
5E
(P)
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINEnon-polymer803.41Chemie (GTG)
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G
(A)
PYROPHOSPHATE 2-non-polymer176.01Chemie (POP)
8H
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
A: 1 - 2263 (UniProt: A5HC98)
PDBExternal DatabaseDetails
Lys 34His 34engineered mutation
Ser 1031-insertion
Gly 1031-insertion
Trp 1031-insertion
Ser 1031-insertion
His 1031-insertion
Pro 1031-insertion
Gln 1031-insertion
Phe 1031-insertion
Glu 1031-insertion
Lys 1031-insertion
Gly 1031-insertion
Ser 1031-insertion
Gly 1031-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight282886.0
Non-Polymers*Number of molecules4
Total formula weight1069.1
All*Total formula weight283955.1
*Water molecules are not included.

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PDB entries from 2026-02-25

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