7OR7
Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ178
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 253 | 28226.5 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | Neurogenic locus notch homolog protein 4 | polymer | 11 | 1334.5 | 1 | UniProt (Q99466) | Homo sapiens | Notch 4,hNotch4 |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-1~{H}-indole-6-carboxamide | non-polymer | 374.5 | 1 | Chemie (0B7) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29561.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 434.2 | |
| All* | Total formula weight | 29995.2 |
