7OPD
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-directed RNA polymerase II subunit RPB1 | polymer | 1970 | 217450.1 | 1 | UniProt (P11414) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB | Sus scrofa (Pig) | |
| 2 | B | DNA-directed RNA polymerase subunit beta | polymer | 1174 | 134041.4 | 1 | UniProt (I3LGP4) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB | Sus scrofa (Pig) | |
| 3 | C | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (I3LCH3) Pfam (PF01193) Pfam (PF01000) In PDB | Sus scrofa (Pig) | |
| 4 | D | RPOL4c domain-containing protein | polymer | 142 | 16331.3 | 1 | UniProt (A0A287ADR4) Pfam (PF03874) In PDB | Sus scrofa (Pig) | |
| 5 | E | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (I3LSI7) Pfam (PF03871) Pfam (PF01191) In PDB | Sus scrofa (Pig) | RPB5 homolog |
| 6 | F | DNA-directed RNA polymerase II subunit F | polymer | 127 | 14477.0 | 1 | UniProt (F1SKN8) Pfam (PF01192) UniProt (by SIFTS) (A0A4X1VEK9) In PDB | Sus scrofa (Pig) | DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog |
| 7 | G | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (I3LJZ9) In PDB | Sus scrofa (Pig) | |
| 8 | H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (A0A4X1ULF2) Pfam (PF03870) UniProt (by SIFTS) (I3LCB2) In PDB | Sus scrofa (Pig) | |
| 9 | I | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) In PDB | Sus scrofa (Pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 10 | J | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A4X1VYD0) Pfam (PF01194) In PDB | Sus scrofa (Pig) | |
| 11 | K | RNA_pol_L_2 domain-containing protein | polymer | 117 | 13310.3 | 1 | UniProt (A0A4X1UK25) Pfam (PF13656) UniProt (by SIFTS) (F1RKE4) In PDB | Sus scrofa (Pig) | |
| 12 | L | RNA polymerase II subunit K | polymer | 58 | 7018.2 | 1 | UniProt (I3LN51) Pfam (PF03604) UniProt (by SIFTS) (A0A4X1TRS6) In PDB | Sus scrofa (Pig) | |
| 13 | M | Transcription elongation factor SPT6 | polymer | 1729 | 199603.0 | 1 | UniProt (Q7KZ85) Pfam (PF14632) Pfam (PF14641) Pfam (PF22706) Pfam (PF14639) Pfam (PF14635) Pfam (PF17674) Pfam (PF00575) Pfam (PF14633) In PDB | Homo sapiens (Human) | hSPT6,Histone chaperone suppressor of Ty6,Tat-cotransactivator 2 protein,Tat-CT2 protein |
| 14 | N | NTS | polymer | 47 | 14494.3 | 1 | Homo sapiens | ||
| 15 | P | RNA | polymer | 45 | 14490.8 | 1 | Homo sapiens | ||
| 16 | R | LEO1 helix | polymer | 40 | 3422.2 | 1 | Homo sapiens (Human) | ||
| 17 | S | RNA polymerase-associated protein CTR9 homolog | polymer | 1179 | 134510.2 | 1 | UniProt (Q6PD62) Pfam (PF13374) Pfam (PF13181) In PDB | Homo sapiens (Human) | SH2 domain-binding protein 1 |
| 18 | T | TS | polymer | 47 | 14269.1 | 1 | Homo sapiens | ||
| 19 | U | RNA polymerase-associated protein LEO1 | polymer | 666 | 75514.2 | 1 | UniProt (Q8WVC0) Pfam (PF04004) In PDB | Homo sapiens (Human) | Replicative senescence down-regulated leo1-like protein |
| 20 | V | RNA polymerase II-associated factor 1 homolog | polymer | 531 | 60052.7 | 1 | UniProt (Q8N7H5) Pfam (PF03985) In PDB | Homo sapiens (Human) | hPAF1,Pancreatic differentiation protein 2 |
| 21 | Y | WD repeat-containing protein 61 | polymer | 305 | 33617.5 | 1 | UniProt (Q9GZS3) Pfam (PF00400) In PDB | Homo sapiens (Human) | Meiotic recombination REC14 protein homolog,SKI8 homolog,Ski8 |
| 22 | Z | Parafibromin | polymer | 531 | 60673.5 | 1 | UniProt (Q6P1J9) Pfam (PF16050) Pfam (PF05179) In PDB | Homo sapiens (Human) | Cell division cycle protein 73 homolog,Hyperparathyroidism 2 protein |
| 23 | a | DNA excision repair protein ERCC-8 | polymer | 396 | 44107.2 | 1 | UniProt (Q13216) Pfam (PF00400) In PDB | Homo sapiens (Human) | Cockayne syndrome WD repeat protein CSA |
| 24 | b | DNA excision repair protein ERCC-6 | polymer | 1496 | 168973.8 | 1 | UniProt (Q03468) Pfam (PF00176) Pfam (PF00271) In PDB | Homo sapiens (Human) | ATP-dependent helicase ERCC6,Cockayne syndrome protein CSB |
| 25 | c | UV-stimulated scaffold protein A | polymer | 712 | 80993.9 | 1 | UniProt (Q2YD98) Pfam (PF20867) Pfam (PF09740) In PDB | Homo sapiens (Human) | |
| 26 | d | DNA damage-binding protein 1 | polymer | 1143 | 127369.7 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (Human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 27 | e | Cullin-4A | polymer | 762 | 88086.6 | 1 | UniProt (Q13619) Pfam (PF00888) Pfam (PF10557) In PDB | Homo sapiens (Human) | CUL-4A |
| 28 | f | E3 ubiquitin-protein ligase RBX1 | polymer | 108 | 12290.0 | 1 | UniProt (P62878) Pfam (PF12678) In PDB | Mus musculus (House mouse) | E3 ubiquitin-protein transferase RBX1,RING finger protein 75,RING-box protein 1,Rbx1 |
| 29 | A, B, C, I, J... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 30 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
M: 1 - 1726 (UniProt: Q7KZ85)
S: 1 - 1173 (UniProt: Q6PD62)
b: 1 - 1493 (UniProt: Q03468)
c: 1 - 709 (UniProt: Q2YD98)
d: 1 - 1140 (UniProt: Q16531)
e: 1 - 759 (UniProt: Q13619)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 1174 | - | expression tag |
| Asn 1175 | - | expression tag |
| Leu 1176 | - | expression tag |
| Tyr 1177 | - | expression tag |
| Phe 1178 | - | expression tag |
| Gln 1179 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Arg 538 | Lys 538 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 1649853.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 1650400.8 |
