7OOT
X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interferon regulatory factor 4 | polymer | 141 | 16306.5 | 2 | UniProt (Q15306) Pfam (PF00605) | Homo sapiens (Human) | IRF-4,Lymphocyte-specific interferon regulatory factor,LSIRF,Multiple myeloma oncogene 1,NF-EM5 |
| 2 | C (C) | DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3') | polymer | 20 | 6145.0 | 1 | Mus musculus | ||
| 3 | D (E) | DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3') | polymer | 20 | 6121.9 | 1 | Mus musculus | ||
| 4 | E (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | F, G, H, I (A, B, C, E) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 139 (UniProt: Q15306)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Ala 10 | - | expression tag |
| Leu 11 | - | expression tag |
| Glu 12 | - | expression tag |
| Val 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Phe 15 | - | expression tag |
| Gln 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Gly 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44879.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 44974.9 |
