7ONW
Crystal structure of PBP3 from E. coli in complex with AIC499
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidoglycan D,D-transpeptidase FtsI | polymer | 564 | 61102.6 | 1 | UniProt (P0AD68) Pfam (PF03717) Pfam (PF00905) In PDB | Escherichia coli (strain K12) | Essential cell division protein FtsI,Murein transpeptidase,Penicillin-binding protein 3,PBP-3,Peptidoglycan synthase FtsI |
2 | A | (2S)-2-[(Z)-[1-(2-azanyl-1,3-thiazol-4-yl)-2-[[(2S)-3-methyl-1-oxidanylidene-3-(sulfooxyamino)butan-2-yl]amino]-2-oxidanylidene-ethylidene]amino]oxy-3-[4-[N-[(3R)-piperidin-3-yl]carbamimidoyl]phenoxy]propanoic acid | non-polymer | 670.7 | 1 | Chemie (VL5) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
5 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A: 49 - 588 (UniProt: P0AD68)
PDB | External Database | Details |
---|---|---|
Met 25 | - | initiating methionine |
Gly 26 | - | expression tag |
Ser 27 | - | expression tag |
Ser 28 | - | expression tag |
His 29 | - | expression tag |
His 30 | - | expression tag |
His 31 | - | expression tag |
His 32 | - | expression tag |
His 33 | - | expression tag |
His 34 | - | expression tag |
Ser 35 | - | expression tag |
Ser 36 | - | expression tag |
Gly 37 | - | expression tag |
Leu 38 | - | expression tag |
Val 39 | - | expression tag |
Pro 40 | - | expression tag |
Arg 41 | - | expression tag |
Gly 42 | - | expression tag |
Ser 43 | - | expression tag |
His 44 | - | expression tag |
Met 45 | - | expression tag |
Ala 46 | - | expression tag |
Ser 47 | - | expression tag |
Met 48 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 61102.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1097.0 | |
All* | Total formula weight | 62199.6 |