7ONU
Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-hydroxyacyl-CoA dehydrogenase type-2 | polymer | 261 | 26947.0 | 4 | UniProt (Q99714) Pfam (PF00106) | Homo sapiens (Human) | 17-beta-estradiol 17-dehydrogenase,2-methyl-3-hydroxybutyryl-CoA dehydrogenase,MHBD,3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)),3-hydroxy-2-methylbutyryl-CoA dehydrogenase,3-hydroxyacyl-CoA dehydrogenase type II,3alpha(or 20beta)-hydroxysteroid dehydrogenase,7-alpha-hydroxysteroid dehydrogenase,Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,Mitochondrial ribonuclease P protein 2,Mitochondrial RNase P protein 2,Short chain dehydrogenase/reductase family 5C member 1,Short-chain type dehydrogenase/reductase XH98G2,Type II HADH |
| 2 | E (E) | Mitochondrial ribonuclease P catalytic subunit | polymer | 541 | 62458.4 | 1 | UniProt (O15091) Pfam (PF16953) | Homo sapiens (Human) | Mitochondrial ribonuclease P protein 3,Mitochondrial RNase P protein 3,Protein only RNase P catalytic subunit |
| 3 | F (F) | tRNA methyltransferase 10 homolog C | polymer | 367 | 42942.5 | 1 | UniProt (Q7L0Y3) Pfam (PF01746) | Homo sapiens (Human) | HBV pre-S2 trans-regulated protein 2,Mitochondrial ribonuclease P protein 1,Mitochondrial RNase P protein 1,RNA (guanine-9-)-methyltransferase domain-containing protein 1,Renal carcinoma antigen NY-REN-49,mRNA methyladenosine-N(1)-methyltransferase,tRNA (adenine(9)-N(1))-methyltransferase,tRNA (guanine(9)-N(1))-methyltransferase |
| 4 | G (T) | Mitochondrial Precursor tRNA-Tyr | polymer | 128 | 41490.6 | 1 | Homo sapiens (Human) | ||
| 5 | H, I, J, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 6 | L (E) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | M (E) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
E: 46 - 583 (UniProt: O15091)
F: 40 - 403 (UniProt: Q7L0Y3)
| PDB | External Database | Details |
|---|---|---|
| Ser 43 | - | expression tag |
| Asn 44 | - | expression tag |
| Ala 45 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 37 | - | expression tag |
| Asn 38 | - | expression tag |
| Ala 39 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 254679.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2743.4 | |
| All* | Total formula weight | 257423.0 |
