7ONN
Crystal structure of PBP3 transpeptidase domain from E. coli in complex with AIC499
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidoglycan D,D-transpeptidase FtsI | polymer | 410 | 43696.8 | 1 | UniProt (P0AD68) Pfam (PF03717) Pfam (PF00905) | Escherichia coli (strain K12) | Essential cell division protein FtsI,Murein transpeptidase,Penicillin-binding protein 3,PBP-3,Peptidoglycan synthase FtsI,Essential cell division protein FtsI,Murein transpeptidase,Penicillin-binding protein 3,PBP-3,Peptidoglycan synthase FtsI,Essential cell division protein FtsI,Murein transpeptidase,Penicillin-binding protein 3,PBP-3,Peptidoglycan synthase FtsI |
| 2 | B (A) | (2S)-2-[(Z)-[1-(2-azanyl-1,3-thiazol-4-yl)-2-[[(2S)-3-methyl-1-oxidanylidene-3-(sulfooxyamino)butan-2-yl]amino]-2-oxidanylidene-ethylidene]amino]oxy-3-[4-[N-[(3R)-piperidin-3-yl]carbamimidoyl]phenoxy]propanoic acid | non-polymer | 670.7 | 1 | Chemie (VL5) | |||
| 3 | C, D (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 2 | Chemie (12P) | |||
| 4 | E (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 68 - 88 (UniProt: P0AD68)
A: 164 - 203 (UniProt: P0AD68)
A: 228 - 570 (UniProt: P0AD68)
A: 164 - 203 (UniProt: P0AD68)
| PDB | External Database | Details |
|---|---|---|
| Gly 89 | - | linker |
| Gly 90 | - | linker |
| Gly 91 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 225 | - | linker |
| Gly 226 | - | linker |
| Gly 227 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43696.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1764.0 | |
| All* | Total formula weight | 45460.8 |
