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7OM1

Tankyrase 2 in complex with an inhibitor (OUL220)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAA, BBBPoly [ADP-ribose] polymerase tankyrase-2polymer17119482.12UniProt (Q9H2K2)
Pfam (PF00644)
In PDB
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
2A, BPoly [ADP-ribose] polymerase tankyrase-2polymer485364.02UniProt (Q9H2K2)
In PDB
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
3AAA, BBB8-methoxy-4~{H}-thieno[2,3-c]isoquinolin-5-onenon-polymer231.32Chemie (1OI)
4AAA, BBBZINC IONnon-polymer65.42Chemie (ZN)
5AAA, A, BBBSULFATE IONnon-polymer96.14Chemie (SO4)
6A, BBBGLYCEROLnon-polymer92.12Chemie (GOL)
7waterwater18.0357Chemie (HOH)
Sequence modifications
AAA, BBB: 946 - 1114 (UniProt: Q9H2K2)
PDBExternal DatabaseDetails
Ser 944-expression tag
Met 945-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight49692.2
Non-Polymers*Number of molecules10
Total formula weight1161.8
All*Total formula weight50854.0
*Water molecules are not included.

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PDB entries from 2024-07-17

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