7OLE

Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	RuvB-like 1	polymer	456	50296.9	3	UniProt (Q9Y265) Pfam (PF06068) Pfam (PF17856) In PDB	Homo sapiens (Human)	49 kDa TATA box-binding protein-interacting protein,49 kDa TBP-interacting protein,54 kDa erythrocyte cytosolic protein,ECP-54,INO80 complex subunit H,Nuclear matrix protein 238,NMP 238,Pontin 52,TIP49a,TIP60-associated protein 54-alpha,TAP54-alpha
2	B, D, F	RuvB-like 2	polymer	463	51222.5	3	UniProt (Q9Y230) Pfam (PF06068) Pfam (PF17856) In PDB	Homo sapiens (Human)	48 kDa TATA box-binding protein-interacting protein,48 kDa TBP-interacting protein,51 kDa erythrocyte cytosolic protein,ECP-51,INO80 complex subunit J,Repressing pontin 52,Reptin 52,TIP49b,TIP60-associated protein 54-beta,TAP54-beta
3	H	TELO2-interacting protein 1 homolog,TELO2-interacting protein 1 homolog,TTI1	polymer	1733	176844.3	1	UniProt (O43156) Pfam (PF21547) In PDB	Homo sapiens (Human)	Protein SMG10
4	J	TELO2-interacting protein 2,TELO2-interacting protein 2,TTI2	polymer	964	95633.8	1	UniProt (Q6NXR4) Pfam (PF10521) In PDB	Homo sapiens (Human)
5	K	Telomere length regulation protein TEL2 homolog	polymer	491	53424.2	1	UniProt (Q9Y4R8) In PDB	Homo sapiens (Human)	Protein clk-2 homolog,hCLK2,Protein clk-2 homolog,hCLK2,Protein clk-2 homolog,hCLK2,Protein clk-2 homolog,hCLK2
6	B, C, D, E, F	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	5	Chemie (ADP)

Sequence modifications

H: -1050 - 38 (UniProt: O43156)
H: 39 - 682 (PDB: 7OLE)
J: -464 - 43 (UniProt: Q6NXR4)
J: 44 - 508 (PDB: 7OLE)
K: 1 - 38 (UniProt: Q9Y4R8)
K: 39 - 48 (PDB: 7OLE)
K: 48 - 66 (UniProt: Q9Y4R8)
K: 67 - 74 (PDB: 7OLE)
K: 74 - 138 (UniProt: Q9Y4R8)
K: 139 - 156 (PDB: 7OLE)
K: 156 - 444 (UniProt: Q9Y4R8)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.