7OJO
Tankyrase 2 in complex with two small molecule fragments
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | AAA, BBB | Poly [ADP-ribose] polymerase tankyrase-2 | polymer | 171 | 19482.1 | 2 | UniProt (Q9H2K2) Pfam (PF00644) In PDB | Homo sapiens (human) | ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein |
| 2 | A, B | Poly [ADP-ribose] polymerase tankyrase-2 | polymer | 48 | 5364.0 | 2 | UniProt (Q9H2K2) In PDB | Homo sapiens (human) | ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein |
| 3 | AAA, BBB | quinazolin-4(3H)-one | non-polymer | 146.1 | 2 | Chemie (WQG) | |||
| 4 | AAA, BBB | 4-acetamido-~{N}-(2-methoxyphenyl)benzamide | non-polymer | 284.3 | 2 | Chemie (VGZ) | |||
| 5 | AAA, BBB | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | A, BBB, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 946 - 1114 (UniProt: Q9H2K2)
| PDB | External Database | Details |
|---|---|---|
| Ser 944 | - | expression tag |
| Met 945 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49692.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1568.1 | |
| All* | Total formula weight | 51260.3 |
