7OIC
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 16S rRNA | polymer | 1559 | 500043.6 | 1 | Homo sapiens | ||
| 2 | B (B) | mitochondrial Val tRNA | polymer | 69 | 22022.1 | 1 | GenBank (1485738021) | Homo sapiens (human) | |
| 3 | C (D) | Large ribosomal subunit protein uL2m | polymer | 305 | 33355.9 | 1 | UniProt (Q5T653) Pfam (PF00181) Pfam (PF03947) | Homo sapiens (human) | |
| 4 | D (E) | Large ribosomal subunit protein uL3m | polymer | 348 | 38689.6 | 1 | UniProt (P09001) Pfam (PF00297) | Homo sapiens (human) | |
| 5 | E (F) | Large ribosomal subunit protein uL4m | polymer | 311 | 34970.2 | 1 | UniProt (Q9BYD3) Pfam (PF00573) | Homo sapiens (human) | |
| 6 | F (H) | Large ribosomal subunit protein bL9m | polymer | 267 | 30296.4 | 1 | UniProt (Q9BYD2) Pfam (PF01281) Pfam (PF22078) | Homo sapiens (human) | |
| 7 | G (I) | Large ribosomal subunit protein uL10m | polymer | 261 | 29322.5 | 1 | UniProt (Q7Z7H8) Pfam (PF00466) | Homo sapiens (human) | |
| 8 | H (J) | Large ribosomal subunit protein uL11m | polymer | 192 | 20716.2 | 1 | UniProt (Q9Y3B7) Pfam (PF03946) Pfam (PF00298) | Homo sapiens (human) | |
| 9 | I (K) | Large ribosomal subunit protein uL13m | polymer | 178 | 20723.0 | 1 | UniProt (Q9BYD1) Pfam (PF00572) | Homo sapiens (human) | |
| 10 | J (L) | Large ribosomal subunit protein uL14m | polymer | 145 | 15973.7 | 1 | UniProt (Q6P1L8) Pfam (PF00238) | Homo sapiens (human) | |
| 11 | K (M) | Large ribosomal subunit protein uL15m | polymer | 296 | 33473.8 | 1 | UniProt (Q9P015) Pfam (PF00828) | Homo sapiens (human) | |
| 12 | L (N) | Large ribosomal subunit protein uL16m | polymer | 251 | 28496.3 | 1 | UniProt (Q9NX20) Pfam (PF00252) | Homo sapiens (human) | |
| 13 | M (O) | Large ribosomal subunit protein bL17m | polymer | 175 | 20083.3 | 1 | UniProt (Q9NRX2) Pfam (PF01196) | Homo sapiens (human) | |
| 14 | N (P) | Large ribosomal subunit protein uL18m | polymer | 180 | 20607.6 | 1 | UniProt (Q9H0U6) Pfam (PF00861) | Homo sapiens (human) | |
| 15 | O (Q) | Large ribosomal subunit protein bL19m | polymer | 292 | 33585.0 | 1 | UniProt (P49406) Pfam (PF01245) | Homo sapiens (human) | |
| 16 | P (R) | Large ribosomal subunit protein bL20m | polymer | 149 | 17479.7 | 1 | UniProt (Q9BYC9) Pfam (PF00453) | Homo sapiens (human) | |
| 17 | Q (S) | Large ribosomal subunit protein bL21m | polymer | 205 | 22847.7 | 1 | UniProt (Q7Z2W9) Pfam (PF00829) | Homo sapiens (human) | |
| 18 | R (T) | Large ribosomal subunit protein uL22m | polymer | 206 | 23683.7 | 1 | UniProt (Q9NWU5) Pfam (PF00237) | Homo sapiens (human) | |
| 19 | S (U) | Large ribosomal subunit protein uL23m | polymer | 153 | 17807.2 | 1 | UniProt (Q16540) Pfam (PF00276) | Homo sapiens (human) | |
| 20 | T (V) | Large ribosomal subunit protein uL24m | polymer | 216 | 24953.9 | 1 | UniProt (Q96A35) Pfam (PF00467) Pfam (PF17136) | Homo sapiens (human) | |
| 21 | U (W) | Large ribosomal subunit protein bL27m | polymer | 148 | 16102.9 | 1 | UniProt (Q9P0M9) Pfam (PF01016) | Homo sapiens (human) | |
| 22 | V (X) | Large ribosomal subunit protein bL28m | polymer | 256 | 30090.7 | 1 | UniProt (Q13084) Pfam (PF00830) | Homo sapiens (human) | |
| 23 | W (Y) | Large ribosomal subunit protein uL29m | polymer | 250 | 29508.5 | 1 | UniProt (Q9HD33) Pfam (PF06984) | Homo sapiens (human) | |
| 24 | X (Z) | Large ribosomal subunit protein uL30m | polymer | 161 | 18582.8 | 1 | UniProt (Q8TCC3) Pfam (PF00327) | Homo sapiens (human) | |
| 25 | Y (0) | Large ribosomal subunit protein bL32m | polymer | 188 | 21437.8 | 1 | UniProt (Q9BYC8) Pfam (PF01783) | Homo sapiens (human) | |
| 26 | Z (1) | Large ribosomal subunit protein bL33m | polymer | 65 | 7635.2 | 1 | UniProt (O75394) Pfam (PF00471) | Homo sapiens (human) | |
| 27 | AA (2) | Large ribosomal subunit protein bL34m | polymer | 92 | 10183.9 | 1 | UniProt (Q9BQ48) Pfam (PF00468) | Homo sapiens (human) | |
| 28 | BA (3) | Large ribosomal subunit protein bL35m | polymer | 188 | 21558.5 | 1 | UniProt (Q9NZE8) Pfam (PF01632) | Homo sapiens (human) | |
| 29 | CA (4) | Large ribosomal subunit protein bL36m | polymer | 103 | 11809.3 | 1 | UniProt (Q9P0J6) Pfam (PF00444) | Homo sapiens (human) | |
| 30 | DA (5) | Large ribosomal subunit protein mL37 | polymer | 423 | 48183.3 | 1 | UniProt (Q9BZE1) Pfam (PF07147) | Homo sapiens (human) | |
| 31 | EA (6) | Large ribosomal subunit protein mL38 | polymer | 380 | 44659.4 | 1 | UniProt (Q96DV4) Pfam (PF01161) | Homo sapiens (human) | |
| 32 | FA (7) | Large ribosomal subunit protein mL39 | polymer | 338 | 38764.8 | 1 | UniProt (Q9NYK5) | Homo sapiens (human) | |
| 33 | GA (8) | Large ribosomal subunit protein mL40 | polymer | 206 | 24534.4 | 1 | UniProt (Q9NQ50) Pfam (PF09812) | Homo sapiens (human) | |
| 34 | HA (9) | Large ribosomal subunit protein mL41 | polymer | 137 | 15404.7 | 1 | UniProt (Q8IXM3) Pfam (PF09809) | Homo sapiens (human) | |
| 35 | IA (a) | Large ribosomal subunit protein mL42 | polymer | 142 | 16691.2 | 1 | UniProt (Q9Y6G3) Pfam (PF10210) | Homo sapiens (human) | |
| 36 | JA (b) | Large ribosomal subunit protein mL43 | polymer | 215 | 23457.8 | 1 | UniProt (Q8N983) Pfam (PF05047) | Homo sapiens (human) | |
| 37 | KA (c) | Large ribosomal subunit protein mL44 | polymer | 332 | 37583.3 | 1 | UniProt (Q9H9J2) Pfam (PF22935) Pfam (PF22892) | Homo sapiens (human) | |
| 38 | LA (d) | 39S ribosomal protein L45, mitochondrial | polymer | 306 | 35402.9 | 1 | UniProt (Q9BRJ2) Pfam (PF04280) | Homo sapiens (human) | MRP-L45,Mitochondrial large ribosomal subunit protein mL45 |
| 39 | MA (e) | Large ribosomal subunit protein mL46 | polymer | 279 | 31748.1 | 1 | UniProt (Q9H2W6) Pfam (PF11788) | Homo sapiens (human) | |
| 40 | NA (f) | Large ribosomal subunit protein mL48 | polymer | 212 | 23970.8 | 1 | UniProt (Q96GC5) Pfam (PF00338) | Homo sapiens (human) | |
| 41 | OA (g) | Large ribosomal subunit protein mL49 | polymer | 166 | 19225.0 | 1 | UniProt (Q13405) Pfam (PF05046) | Homo sapiens (human) | |
| 42 | PA (h) | Large ribosomal subunit protein mL50 | polymer | 158 | 18349.9 | 1 | UniProt (Q8N5N7) Pfam (PF10501) | Homo sapiens (human) | |
| 43 | QA (i) | Large ribosomal subunit protein mL51 | polymer | 128 | 15125.9 | 1 | UniProt (Q4U2R6) Pfam (PF10244) | Homo sapiens (human) | |
| 44 | RA (j) | Large ribosomal subunit protein mL52 | polymer | 123 | 13682.7 | 1 | UniProt (Q86TS9) Pfam (PF18699) | Homo sapiens (human) | |
| 45 | SA (k) | Large ribosomal subunit protein mL53 | polymer | 112 | 12125.9 | 1 | UniProt (Q96EL3) Pfam (PF10780) | Homo sapiens (human) | |
| 46 | TA (l) | Large ribosomal subunit protein mL54 | polymer | 138 | 15844.2 | 1 | UniProt (Q6P161) Pfam (PF08561) | Homo sapiens (human) | |
| 47 | UA (m) | Large ribosomal subunit protein mL55 | polymer | 128 | 15160.4 | 1 | UniProt (Q7Z7F7) Pfam (PF09776) | Homo sapiens (human) | |
| 48 | VA (o) | Large ribosomal subunit protein mL63 | polymer | 102 | 12292.3 | 1 | UniProt (Q9BQC6) Pfam (PF14978) | Homo sapiens (human) | |
| 49 | WA (p) | Large ribosomal subunit protein mL62 | polymer | 206 | 23674.2 | 1 | UniProt (Q14197) Pfam (PF00472) | Homo sapiens (human) | |
| 50 | XA (q) | Large ribosomal subunit protein mL64 | polymer | 222 | 25426.9 | 1 | UniProt (Q8TAE8) Pfam (PF10147) | Homo sapiens (human) | |
| 51 | YA (r) | Large ribosomal subunit protein mL66 | polymer | 196 | 22224.1 | 1 | UniProt (Q9NVS2) Pfam (PF01084) | Homo sapiens (human) | |
| 52 | ZA (s) | Large ribosomal subunit protein mL65 | polymer | 439 | 50429.6 | 1 | UniProt (Q9NP92) Pfam (PF07147) | Homo sapiens (human) | |
| 53 | AB (u) | Mitochondrial assembly of ribosomal large subunit protein 1 | polymer | 234 | 26203.1 | 1 | UniProt (Q96EH3) Pfam (PF02410) | Homo sapiens (human) | |
| 54 | BB (v) | MIEF1 upstream open reading frame protein | polymer | 70 | 8460.8 | 1 | UniProt (L0R8F8) Pfam (PF05347) | Homo sapiens (human) | |
| 55 | CB (w) | Acyl carrier protein, mitochondrial | polymer | 156 | 17434.3 | 1 | UniProt (O14561) Pfam (PF00550) | Homo sapiens (human) | |
| 56 | DB (x) | 5-cytosine rRNA methyltransferase NSUN4 | polymer | 384 | 43187.4 | 1 | UniProt (Q96CB9) Pfam (PF01189) | Homo sapiens (human) | |
| 57 | EB (y) | Transcription termination factor 4, mitochondrial | polymer | 381 | 44012.5 | 1 | UniProt (Q7Z6M4) Pfam (PF02536) | Homo sapiens (human) | |
| 58 | FB (C) | RNA pCpA | polymer | 2 | 589.4 | 1 | Homo sapiens | ||
| 59 | AC, AD, AE, BC, BD... (A, F, M, W, g) | MAGNESIUM ION | non-polymer | 24.3 | 76 | Chemie (MG) | |||
| 60 | BE, EE, FE (I, 0, 4) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 61 | HE (v) | 4'-PHOSPHOPANTETHEINE | non-polymer | 358.3 | 1 | Chemie (PNS) | |||
| 62 | IE (x) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) |
Sequence modifications
X: 1 - 256 (UniProt: Q13084)
| PDB | External Database | Details |
|---|---|---|
| Ala 148 | Thr 148 | conflict |
| Ser 149 | Pro 149 | conflict |
| Gly 150 | Lys 150 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 58 |
| Total formula weight | 1879890.2 | |
| Non-Polymers* | Number of molecules | 81 |
| Total formula weight | 2800.2 | |
| All* | Total formula weight | 1882690.4 |
