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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7OI7

Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1D39S ribosomal protein L2, mitochondrialpolymer30533355.91UniProt (Q5T653)
Pfam (PF03947)
Pfam (PF00181)
In PDB		Homo sapiens (Human)MRP-L2,Mitochondrial large ribosomal subunit protein uL2m
2E39S ribosomal protein L3, mitochondrialpolymer34838689.61UniProt (P09001)
Pfam (PF00297)
In PDB		Homo sapiens (Human)MRP-L3,Mitochondrial large ribosomal subunit protein uL3m
3F39S ribosomal protein L4, mitochondrialpolymer31134970.21UniProt (Q9BYD3)
Pfam (PF00573)
In PDB		Homo sapiens (Human)MRP-L4,Mitochondrial large ribosomal subunit protein uL4m
4H39S ribosomal protein L9, mitochondrialpolymer26730296.41UniProt (Q9BYD2)
Pfam (PF01281)
Pfam (PF22078)
In PDB		Homo sapiens (Human)MRP-L9,Mitochondrial large ribosomal subunit protein bL9m
5I39S ribosomal protein L10, mitochondrialpolymer26129322.51UniProt (Q7Z7H8)
Pfam (PF00466)
In PDB		Homo sapiens (Human)MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m
6J39S ribosomal protein L11, mitochondrialpolymer19220716.21UniProt (Q9Y3B7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Homo sapiens (Human)MRP-L11,Mitochondrial large ribosomal subunit protein uL11m
7K39S ribosomal protein L13, mitochondrialpolymer17820723.01UniProt (Q9BYD1)
Pfam (PF00572)
In PDB		Homo sapiens (Human)MRP-L13,Mitochondrial large ribosomal subunit protein uL13m
8L39S ribosomal protein L14, mitochondrialpolymer14515973.71UniProt (Q6P1L8)
Pfam (PF00238)
In PDB		Homo sapiens (Human)MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m
9M39S ribosomal protein L15, mitochondrialpolymer29633473.81UniProt (Q9P015)
Pfam (PF00828)
In PDB		Homo sapiens (Human)MRP-L15,Mitochondrial large ribosomal subunit protein uL15m
10N39S ribosomal protein L16, mitochondrialpolymer25128496.31UniProt (Q9NX20)
Pfam (PF00252)
In PDB		Homo sapiens (Human)MRP-L16,Mitochondrial large ribosomal subunit protein uL16m
11O39S ribosomal protein L17, mitochondrialpolymer17520083.31UniProt (Q9NRX2)
Pfam (PF01196)
In PDB		Homo sapiens (Human)MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m
12P39S ribosomal protein L18, mitochondrialpolymer18020607.61UniProt (Q9H0U6)
Pfam (PF00861)
In PDB		Homo sapiens (Human)MRP-L18,Mitochondrial large ribosomal subunit protein uL18m
13Q39S ribosomal protein L19, mitochondrialpolymer29233585.01UniProt (P49406)
Pfam (PF01245)
In PDB		Homo sapiens (Human)MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m
14R39S ribosomal protein L20, mitochondrialpolymer14917479.71UniProt (Q9BYC9)
Pfam (PF00453)
In PDB		Homo sapiens (Human)MRP-L20,Mitochondrial large ribosomal subunit protein bL20m
15S39S ribosomal protein L21, mitochondrialpolymer20522847.71UniProt (Q7Z2W9)
Pfam (PF00829)
In PDB		Homo sapiens (Human)MRP-L21,Mitochondrial large ribosomal subunit protein bL21m
16T39S ribosomal protein L22, mitochondrialpolymer20623683.71UniProt (Q9NWU5)
Pfam (PF00237)
In PDB		Homo sapiens (Human)MRP-L22,39S ribosomal protein L25,mitochondrial,MRP-L25,Mitochondrial large ribosomal subunit protein uL22m
17U39S ribosomal protein L23, mitochondrialpolymer15317807.21UniProt (Q16540)
Pfam (PF00276)
In PDB		Homo sapiens (Human)MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like
18V39S ribosomal protein L24, mitochondrialpolymer21624953.91UniProt (Q96A35)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Homo sapiens (Human)MRP-L24,Mitochondrial large ribosomal subunit protein uL24m
19W39S ribosomal protein L27, mitochondrialpolymer14816102.91UniProt (Q9P0M9)
Pfam (PF01016)
In PDB		Homo sapiens (Human)MRP-L27,Mitochondrial large ribosomal subunit protein bL27m
20X39S ribosomal protein L28, mitochondrialpolymer25630202.91UniProt (Q13084)
Pfam (PF00830)
In PDB		Homo sapiens (Human)MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m
21Y39S ribosomal protein L47, mitochondrialpolymer25029508.51UniProt (Q9HD33)
Pfam (PF06984)
In PDB		Homo sapiens (Human)MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1
22Z39S ribosomal protein L30, mitochondrialpolymer16118582.81UniProt (Q8TCC3)
Pfam (PF00327)
In PDB		Homo sapiens (Human)MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m
23039S ribosomal protein L32, mitochondrialpolymer18821437.81UniProt (Q9BYC8)
Pfam (PF01783)
In PDB		Homo sapiens (Human)MRP-L32,Mitochondrial large ribosomal subunit protein bL32m
24139S ribosomal protein L33, mitochondrialpolymer657635.21UniProt (O75394)
Pfam (PF00471)
In PDB		Homo sapiens (Human)MRP-L33,Mitochondrial large ribosomal subunit protein bL33m
25239S ribosomal protein L34, mitochondrialpolymer9210183.91UniProt (Q9BQ48)
Pfam (PF00468)
In PDB		Homo sapiens (Human)MRP-L34,Mitochondrial large ribosomal subunit protein bL34m
26339S ribosomal protein L35, mitochondrialpolymer18821558.51UniProt (Q9NZE8)
Pfam (PF01632)
In PDB		Homo sapiens (Human)MRP-L35,Mitochondrial large ribosomal subunit protein bL35m
27539S ribosomal protein L37, mitochondrialpolymer42348183.31UniProt (Q9BZE1)
Pfam (PF07147)
In PDB		Homo sapiens (Human)MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37
28639S ribosomal protein L38, mitochondrialpolymer38044659.41UniProt (Q96DV4)
Pfam (PF01161)
In PDB		Homo sapiens (Human)MRP-L38,Mitochondrial large ribosomal subunit protein mL38
29739S ribosomal protein L39, mitochondrialpolymer33838764.81UniProt (Q9NYK5)
In PDB		Homo sapiens (Human)MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39
30839S ribosomal protein L40, mitochondrialpolymer20624534.41UniProt (Q9NQ50)
Pfam (PF09812)
In PDB		Homo sapiens (Human)MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis
31939S ribosomal protein L41, mitochondrialpolymer13715404.71UniProt (Q8IXM3)
Pfam (PF09809)
In PDB		Homo sapiens (Human)MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41
32a39S ribosomal protein L42, mitochondrialpolymer14216691.21UniProt (Q9Y6G3)
Pfam (PF10210)
In PDB		Homo sapiens (Human)MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42
33b39S ribosomal protein L43, mitochondrialpolymer21523457.81UniProt (Q8N983)
Pfam (PF05047)
In PDB		Homo sapiens (Human)MRP-L43,Mitochondrial large ribosomal subunit protein mL43,Mitochondrial ribosomal protein bMRP36a
34c39S ribosomal protein L44, mitochondrialpolymer33237583.31UniProt (Q9H9J2)
Pfam (PF22935)
Pfam (PF22892)
In PDB		Homo sapiens (Human)MRP-L44,Mitochondrial large ribosomal subunit protein mL44
35d39S ribosomal protein L45, mitochondrialpolymer30635402.91UniProt (Q9BRJ2)
Pfam (PF04280)
In PDB		Homo sapiens (Human)MRP-L45,Mitochondrial large ribosomal subunit protein mL45
36e39S ribosomal protein L46, mitochondrialpolymer27931748.11UniProt (Q9H2W6)
Pfam (PF11788)
In PDB		Homo sapiens (Human)MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL
37f39S ribosomal protein L48, mitochondrialpolymer21223970.81UniProt (Q96GC5)
Pfam (PF00338)
In PDB		Homo sapiens (Human)MRP-L48,Mitochondrial large ribosomal subunit protein mL48
38g39S ribosomal protein L49, mitochondrialpolymer16619225.01UniProt (Q13405)
Pfam (PF05046)
In PDB		Homo sapiens (Human)MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1
39h39S ribosomal protein L50, mitochondrialpolymer15818349.91UniProt (Q8N5N7)
Pfam (PF10501)
In PDB		Homo sapiens (Human)MRP-L50,Mitochondrial large ribosomal subunit protein mL50
40i39S ribosomal protein L51, mitochondrialpolymer12815125.91UniProt (Q4U2R6)
Pfam (PF10244)
In PDB		Homo sapiens (Human)MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64
41j39S ribosomal protein L52, mitochondrialpolymer12313682.71UniProt (Q86TS9)
Pfam (PF18699)
In PDB		Homo sapiens (Human)MRP-L52,Mitochondrial large ribosomal subunit protein mL52
42k39S ribosomal protein L53, mitochondrialpolymer11212125.91UniProt (Q96EL3)
Pfam (PF10780)
In PDB		Homo sapiens (Human)MRP-L53,Mitochondrial large ribosomal subunit protein mL53
43l39S ribosomal protein L54, mitochondrialpolymer13815844.21UniProt (Q6P161)
Pfam (PF08561)
In PDB		Homo sapiens (Human)MRP-L54,Mitochondrial large ribosomal subunit protein mL54
44m39S ribosomal protein L55, mitochondrialpolymer12815160.41UniProt (Q7Z7F7)
Pfam (PF09776)
In PDB		Homo sapiens (Human)MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55
45oRibosomal protein 63, mitochondrialpolymer10212292.31UniProt (Q9BQC6)
Pfam (PF14978)
In PDB		Homo sapiens (Human)hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57
46pPeptidyl-tRNA hydrolase ICT1, mitochondrialpolymer20623674.21UniProt (Q14197)
Pfam (PF00472)
In PDB		Homo sapiens (Human)39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62
47qGrowth arrest and DNA damage-inducible proteins-interacting protein 1polymer22225426.91UniProt (Q8TAE8)
Pfam (PF10147)
In PDB		Homo sapiens (Human)39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein
48r39S ribosomal protein S18a, mitochondrialpolymer19622224.11UniProt (Q9NVS2)
Pfam (PF01084)
In PDB		Homo sapiens (Human)S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66
49s39S ribosomal protein S30, mitochondrialpolymer43950429.61UniProt (Q9NP92)
Pfam (PF07147)
In PDB		Homo sapiens (Human)S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9
50uMitochondrial assembly of ribosomal large subunit protein 1polymer23426203.11UniProt (Q96EH3)
Pfam (PF02410)
In PDB		Homo sapiens (Human)
51vMIEF1 upstream open reading frame proteinpolymer708460.81UniProt (L0R8F8)
Pfam (PF05347)
In PDB		Homo sapiens (Human)
52wAcyl carrier protein, mitochondrialpolymer15617434.31UniProt (O14561)
Pfam (PF00550)
In PDB		Homo sapiens (Human)ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit
53A16S rRNApolymer1559500019.61GenBank (1025814679)Homo sapiens (Human)
54Bmitochondrial Val tRNApolymer6922022.11GenBank (1485738021)Homo sapiens
55I, 0ZINC IONnon-polymer65.42Chemie (ZN)
56A, W, gMAGNESIUM IONnon-polymer24.349Chemie (MG)
57v4'-PHOSPHOPANTETHEINEnon-polymer358.31Chemie (PNS)
Sequence modifications
A: 1 - 1559 (GenBank: 1025814679)
PDBExternal DatabaseDetails
U 1437Unk 3109conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains54
Total formula weight1780379.8
Non-Polymers*Number of molecules52
Total formula weight1680.1
All*Total formula weight1782059.9
*Water molecules are not included.

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PDB entries from 2024-06-26

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