7OFK
Ligand complex of RORg LBD
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nuclear receptor ROR-gamma | polymer | 266 | 30901.4 | 1 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
2 | C | Nuclear receptor coactivator 2 | polymer | 16 | 1895.2 | 1 | UniProt (Q15596) In PDB | Homo sapiens (Human) | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
3 | A | (1~{R})-2-ethanoyl-~{N}-[4-[1,1,1,3,3,3-hexakis(fluoranyl)-2-oxidanyl-propan-2-yl]phenyl]-5-methylsulfonyl-1,3-dihydroisoindole-1-carboxamide | non-polymer | 524.4 | 1 | Chemie (VCH) | |||
4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | water | water | 18.0 | 282 | Chemie (HOH) |
Sequence modifications
A: 265 - 507 (UniProt: P51449)
C: 684 - 698 (UniProt: Q15596)
PDB | External Database | Details |
---|---|---|
His 244 | - | expression tag |
Asn 245 | - | expression tag |
His 246 | - | expression tag |
Asn 247 | - | expression tag |
His 248 | - | expression tag |
Asn 249 | - | expression tag |
His 250 | - | expression tag |
Asn 251 | - | expression tag |
His 252 | - | expression tag |
Asn 253 | - | expression tag |
His 254 | - | expression tag |
Asn 255 | - | expression tag |
Gly 256 | - | expression tag |
Gly 257 | - | expression tag |
Glu 258 | - | expression tag |
Asn 259 | - | expression tag |
Leu 260 | - | expression tag |
Tyr 261 | - | expression tag |
Phe 262 | - | expression tag |
Gln 263 | - | expression tag |
Gly 264 | - | expression tag |
Gly 508 | - | expression tag |
Gly 509 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 683 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 32796.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 703.7 | |
All* | Total formula weight | 33500.3 |