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7OFB

Keap1 kelch domain bound to a small molecule fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kelch-like ECH-associated protein 1polymer30433362.31UniProt (Q9Z2X8)
Pfam (PF01344)
Mus musculus (Mouse)Cytosolic inhibitor of Nrf2,INrf2
2B
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3C, D, E, F, G...
(A)
DIMETHYL SULFOXIDEnon-polymer78.16Chemie (DMS)
4I
(A)
~{N},~{N}-diethyl-9-oxidanylidene-fluorene-4-carboxamidenon-polymer279.31Chemie (VCN)
5J
(A)
waterwater18.03Chemie (HOH)
Sequence modifications
A: 322 - 624 (UniProt: Q9Z2X8)
PDBExternal DatabaseDetails
Gly 321-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33362.3
Non-Polymers*Number of molecules8
Total formula weight844.2
All*Total formula weight34206.5
*Water molecules are not included.

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PDB entries from 2025-03-12

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