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7OF2

Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with GTPBP6.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(0)
39S ribosomal protein L32, mitochondrialpolymer18821437.81UniProt (Q9BYC8)
Pfam (PF01783)
Homo sapiens (Human)MRP-L32,Mitochondrial large ribosomal subunit protein bL32m
2B
(1)
39S ribosomal protein L33, mitochondrialpolymer657635.21UniProt (O75394)
Pfam (PF00471)
Homo sapiens (Human)MRP-L33,Mitochondrial large ribosomal subunit protein bL33m
3C
(2)
39S ribosomal protein L34, mitochondrialpolymer9210183.91UniProt (Q9BQ48)
Pfam (PF00468)
Homo sapiens (Human)MRP-L34,Mitochondrial large ribosomal subunit protein bL34m
4D
(3)
39S ribosomal protein L35, mitochondrialpolymer18821558.51UniProt (Q9NZE8)
Pfam (PF01632)
Homo sapiens (Human)MRP-L35,Mitochondrial large ribosomal subunit protein bL35m
5E
(4)
39S ribosomal protein L36, mitochondrialpolymer10311809.31UniProt (Q9P0J6)
Pfam (PF00444)
Homo sapiens (Human)MRP-L36,BRCA1-interacting protein 1,Mitochondrial large ribosomal subunit protein bL36m
6F
(5)
39S ribosomal protein L37, mitochondrialpolymer42348183.31UniProt (Q9BZE1)
Pfam (PF07147)
Homo sapiens (Human)MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37
7G
(6)
39S ribosomal protein L38, mitochondrialpolymer38044659.41UniProt (Q96DV4)
Pfam (PF01161)
Homo sapiens (Human)MRP-L38,Mitochondrial large ribosomal subunit protein mL38
8H
(7)
39S ribosomal protein L39, mitochondrialpolymer33838764.81UniProt (Q9NYK5)Homo sapiens (Human)MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39
9I
(8)
39S ribosomal protein L40, mitochondrialpolymer20624534.41UniProt (Q9NQ50)
Pfam (PF09812)
Homo sapiens (Human)MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis
10J
(9)
39S ribosomal protein L41, mitochondrialpolymer13715404.71UniProt (Q8IXM3)
Pfam (PF09809)
Homo sapiens (Human)MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41
11K
(A)
16S ribosomal RNApolymer1559500061.71Homo sapiens
12L
(B)
mitochondrial tRNAValpolymer6922022.11GenBank (1485738021)Homo sapiens
13M
(C)
Putative GTP-binding protein 6polymer51656984.41UniProt (O43824)
Pfam (PF13167)
Pfam (PF16360)
Pfam (PF01926)
Homo sapiens (Human)Pseudoautosomal GTP-binding protein-like
14N
(D)
39S ribosomal protein L2, mitochondrialpolymer30533355.91UniProt (Q5T653)
Pfam (PF00181)
Pfam (PF03947)
Homo sapiens (Human)MRP-L2,Mitochondrial large ribosomal subunit protein uL2m
15O
(E)
39S ribosomal protein L3, mitochondrialpolymer34838689.61UniProt (P09001)
Pfam (PF00297)
Homo sapiens (Human)MRP-L3,Mitochondrial large ribosomal subunit protein uL3m
16P
(F)
39S ribosomal protein L4, mitochondrialpolymer31134970.21UniProt (Q9BYD3)
Pfam (PF00573)
Homo sapiens (Human)MRP-L4,Mitochondrial large ribosomal subunit protein uL4m
17Q
(H)
39S ribosomal protein L9, mitochondrialpolymer26730296.41UniProt (Q9BYD2)
Pfam (PF01281)
Pfam (PF22078)
Homo sapiens (Human)MRP-L9,Mitochondrial large ribosomal subunit protein bL9m
18R
(I)
39S ribosomal protein L10, mitochondrialpolymer26129322.51UniProt (Q7Z7H8)
Pfam (PF00466)
Homo sapiens (Human)MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m
19S
(J)
39S ribosomal protein L11, mitochondrialpolymer19220716.21UniProt (Q9Y3B7)
Pfam (PF03946)
Pfam (PF00298)
Homo sapiens (Human)MRP-L11,Mitochondrial large ribosomal subunit protein uL11m
20T
(K)
39S ribosomal protein L13, mitochondrialpolymer17820723.01UniProt (Q9BYD1)
Pfam (PF00572)
Homo sapiens (Human)MRP-L13,Mitochondrial large ribosomal subunit protein uL13m
21U
(L)
39S ribosomal protein L14, mitochondrialpolymer14515973.71UniProt (Q6P1L8)
Pfam (PF00238)
Homo sapiens (Human)MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m
22V
(M)
39S ribosomal protein L15, mitochondrialpolymer29633473.81UniProt (Q9P015)
Pfam (PF00828)
Homo sapiens (Human)MRP-L15,Mitochondrial large ribosomal subunit protein uL15m
23W
(N)
39S ribosomal protein L16, mitochondrialpolymer25128496.31UniProt (Q9NX20)
Pfam (PF00252)
Homo sapiens (Human)MRP-L16,Mitochondrial large ribosomal subunit protein uL16m
24X
(O)
39S ribosomal protein L17, mitochondrialpolymer17520083.31UniProt (Q9NRX2)
Pfam (PF01196)
Homo sapiens (Human)MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m
25Y
(P)
39S ribosomal protein L18, mitochondrialpolymer18020607.61UniProt (Q9H0U6)
Pfam (PF00861)
Homo sapiens (Human)MRP-L18,Mitochondrial large ribosomal subunit protein uL18m
26Z
(Q)
39S ribosomal protein L19, mitochondrialpolymer29233585.01UniProt (P49406)
Pfam (PF01245)
Homo sapiens (Human)MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m
27AA
(R)
39S ribosomal protein L20, mitochondrialpolymer14917479.71UniProt (Q9BYC9)
Pfam (PF00453)
Homo sapiens (Human)MRP-L20,Mitochondrial large ribosomal subunit protein bL20m
28BA
(S)
39S ribosomal protein L21, mitochondrialpolymer20522847.71UniProt (Q7Z2W9)
Pfam (PF00829)
Homo sapiens (Human)MRP-L21,Mitochondrial large ribosomal subunit protein bL21m
29CA
(T)
39S ribosomal protein L22, mitochondrialpolymer20623683.71UniProt (Q9NWU5)
Pfam (PF00237)
Homo sapiens (Human)MRP-L22,39S ribosomal protein L25,mitochondrial,MRP-L25,Mitochondrial large ribosomal subunit protein uL22m
30DA
(U)
39S ribosomal protein L23, mitochondrialpolymer15317807.21UniProt (Q16540)
Pfam (PF00276)
Homo sapiens (Human)MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like
31EA
(V)
39S ribosomal protein L24, mitochondrialpolymer21624953.91UniProt (Q96A35)
Pfam (PF00467)
Pfam (PF17136)
Homo sapiens (Human)MRP-L24,Mitochondrial large ribosomal subunit protein uL24m
32FA
(W)
39S ribosomal protein L27, mitochondrialpolymer14816102.91UniProt (Q9P0M9)
Pfam (PF01016)
Homo sapiens (Human)MRP-L27,Mitochondrial large ribosomal subunit protein bL27m
33GA
(X)
39S ribosomal protein L28, mitochondrialpolymer25630202.91UniProt (Q13084)
Pfam (PF00830)
Homo sapiens (Human)MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m
34HA
(Y)
39S ribosomal protein L47, mitochondrialpolymer25029508.51UniProt (Q9HD33)
Pfam (PF06984)
Homo sapiens (Human)MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1
35IA
(Z)
39S ribosomal protein L30, mitochondrialpolymer16118582.81UniProt (Q8TCC3)
Pfam (PF00327)
Homo sapiens (Human)MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m
36JA
(a)
39S ribosomal protein L42, mitochondrialpolymer14216691.21UniProt (Q9Y6G3)
Pfam (PF10210)
Homo sapiens (Human)MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42
37KA
(b)
39S ribosomal protein L43, mitochondrialpolymer21523457.81UniProt (Q8N983)
Pfam (PF05047)
Homo sapiens (Human)MRP-L43,Mitochondrial large ribosomal subunit protein mL43,Mitochondrial ribosomal protein bMRP36a
38LA
(c)
39S ribosomal protein L44, mitochondrialpolymer33237583.31UniProt (Q9H9J2)
Pfam (PF22935)
Pfam (PF22892)
Homo sapiens (Human)MRP-L44,Mitochondrial large ribosomal subunit protein mL44
39MA
(d)
39S ribosomal protein L45, mitochondrialpolymer30635402.91UniProt (Q9BRJ2)
Pfam (PF04280)
Homo sapiens (Human)MRP-L45,Mitochondrial large ribosomal subunit protein mL45
40NA
(e)
39S ribosomal protein L46, mitochondrialpolymer27931748.11UniProt (Q9H2W6)
Pfam (PF11788)
Homo sapiens (Human)MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL
41OA
(f)
39S ribosomal protein L48, mitochondrialpolymer21223970.81UniProt (Q96GC5)
Pfam (PF00338)
Homo sapiens (Human)MRP-L48,Mitochondrial large ribosomal subunit protein mL48
42PA
(g)
39S ribosomal protein L49, mitochondrialpolymer16619225.01UniProt (Q13405)
Pfam (PF05046)
Homo sapiens (Human)MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1
43QA
(h)
39S ribosomal protein L50, mitochondrialpolymer15818349.91UniProt (Q8N5N7)
Pfam (PF10501)
Homo sapiens (Human)MRP-L50,Mitochondrial large ribosomal subunit protein mL50
44RA
(i)
39S ribosomal protein L51, mitochondrialpolymer12815125.91UniProt (Q4U2R6)
Pfam (PF10244)
Homo sapiens (Human)MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64
45SA
(j)
39S ribosomal protein L52, mitochondrialpolymer12313682.71UniProt (Q86TS9)
Pfam (PF18699)
Homo sapiens (Human)MRP-L52,Mitochondrial large ribosomal subunit protein mL52
46TA
(k)
39S ribosomal protein L53, mitochondrialpolymer11212125.91UniProt (Q96EL3)
Pfam (PF10780)
Homo sapiens (Human)MRP-L53,Mitochondrial large ribosomal subunit protein mL53
47UA
(l)
39S ribosomal protein L54, mitochondrialpolymer13815844.21UniProt (Q6P161)
Pfam (PF08561)
Homo sapiens (Human)MRP-L54,Mitochondrial large ribosomal subunit protein mL54
48VA
(m)
39S ribosomal protein L55, mitochondrialpolymer12815160.41UniProt (Q7Z7F7)
Pfam (PF09776)
Homo sapiens (Human)MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55
49WA
(o)
Ribosomal protein 63, mitochondrialpolymer10212292.31UniProt (Q9BQC6)
Pfam (PF14978)
Homo sapiens (Human)hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57
50XA
(p)
Peptidyl-tRNA hydrolase ICT1, mitochondrialpolymer20623674.21UniProt (Q14197)
Pfam (PF00472)
Homo sapiens (Human)39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62
51YA
(q)
Growth arrest and DNA damage-inducible proteins-interacting protein 1polymer22225426.91UniProt (Q8TAE8)
Pfam (PF10147)
Homo sapiens (Human)39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein
52ZA
(r)
39S ribosomal protein S18a, mitochondrialpolymer19622224.11UniProt (Q9NVS2)
Pfam (PF01084)
Homo sapiens (Human)S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66
53AB
(s)
39S ribosomal protein S30, mitochondrialpolymer43950429.61UniProt (Q9NP92)
Pfam (PF07147)
Homo sapiens (Human)S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9
54BB
(u)
Mitochondrial assembly of ribosomal large subunit protein 1polymer23426203.11UniProt (Q96EH3)
Pfam (PF02410)
Homo sapiens (Human)
55CB
(v)
MIEF1 upstream open reading frame proteinpolymer708460.81UniProt (L0R8F8)
Pfam (PF05347)
Homo sapiens (Human)
56DB
(w)
Acyl carrier protein, mitochondrialpolymer15617434.31UniProt (O14561)
Pfam (PF00550)
Homo sapiens (Human)ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit
57EB, FB, QE
(0, 4, r)
ZINC IONnon-polymer65.43Chemie (ZN)
58AC, AD, AE, BC, BD...
(A, C, E, W, g)
MAGNESIUM IONnon-polymer24.385Chemie (MG)
59JE, KE, LE
(A, C)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.23Chemie (GTP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains56
Total formula weight1849215.6
Non-Polymers*Number of molecules91
Total formula weight3831.7
All*Total formula weight1853047.3
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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