7OE5
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N5-hydroxycyclohexyl-N3-methyl-1-phenylethyl-1H-pyrazole-3,5-dicarboxamide
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Bromodomain-containing protein 2 | polymer | 115 | 13432.5 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
2 | AAA | 3N-methyl-5N-(4-oxidanylcyclohexyl)-1-[(1S)-1-phenylethyl]pyrazole-3,5-dicarboxamide | non-polymer | 370.4 | 1 | Chemie (V9H) | |||
3 | AAA | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
AAA: 344 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Gly 341 | - | expression tag |
Ser 342 | - | expression tag |
Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13432.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 494.6 | |
All* | Total formula weight | 13927.0 |