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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7OCE

Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, G
(A, C)		Glutamate receptor 1polymer915102661.92UniProt (P19490)
Pfam (PF01094)
Pfam (PF10613)
Pfam (PF00060)		Rattus norvegicus (Norway rat)GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1
2B, E
(B, D)		Glutamate receptor 2polymer86096247.12UniProt (P19491)
Pfam (PF01094)
Pfam (PF10613)
Pfam (PF00060)		Rattus norvegicus (Norway rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
3C, H
(G, E)		Protein cornichon homolog 2polymer18822000.62UniProt (Q5BJU5)
Pfam (PF03311)		Rattus norvegicus (Norway rat)CNIH-2,Cornichon family AMPA receptor auxiliary protein 2,Cornichon-like protein
4D, F
(I, J)		Voltage-dependent calcium channel gamma-8 subunitpolymer42243519.02UniProt (Q8VHW5)
Pfam (PF00822)		Rattus norvegicus (Norway rat)Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8
5I, IA, Q, YA
(A, D, B, C)		6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamidenon-polymer336.34Chemie (E2Q)
PubChem (3272524)
6AA, AB, BA, BB, CB...
(G, C, I, E, A...)		1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.146Chemie (PC1)
PubChem (65146)
PubChem (94190)
PubChem (10417837)
7CA, HB
(G, E)		CHOLESTEROLnon-polymer386.72Chemie (CLR)
PubChem (16219173)
PubChem (16758052)
PubChem (304)
PubChem (176980071)
PubChem (191463)
PubChem (368063)
PubChem (369319)
PubChem (18640088)
PubChem (1715243)
PubChem (40477506)
PubChem (40557614)
PubChem (42579431)
PubChem (42579432)
PubChem (1715244)
PubChem (23423981)
PubChem (45044259)
PubChem (638019)
PubChem (49853509)
PubChem (50990013)
PubChem (44654663)
PubChem (52934537)
PubChem (56621683)
PubChem (1549081)
PubChem (1553803)
PubChem (46937002)
PubChem (57915018)
PubChem (57939063)
PubChem (58428240)
PubChem (58445498)
PubChem (58663286)
PubChem (59450329)
PubChem (59628412)
PubChem (59965215)
PubChem (71234641)
PubChem (59993755)
PubChem (60001463)
PubChem (66634651)
PubChem (59274407)
PubChem (5283629)
PubChem (5284644)
PubChem (68055877)
PubChem (68166463)
PubChem (68315613)
PubChem (5315842)
PubChem (70795838)
PubChem (70797612)
PubChem (70954610)
PubChem (70957185)
PubChem (71463909)
PubChem (68311425)
PubChem (68311398)
PubChem (143173313)
PubChem (177156123)
PubChem (6419195)
PubChem (5997)
PubChem (6994560)
PubChem (7055705)
PubChem (7055706)
PubChem (7059398)
PubChem (7059400)
PubChem (7059635)
PubChem (7103033)
PubChem (7182477)
PubChem (7182478)
PubChem (89951918)
PubChem (90224410)
PubChem (91298236)
PubChem (9909206)
PubChem (10045721)
PubChem (71168115)
PubChem (10134774)
PubChem (10293553)
PubChem (71173031)
PubChem (11003580)
PubChem (11025495)
PubChem (11058155)
PubChem (11463329)
PubChem (1551269)
PubChem (90070115)
PubChem (11868624)
PubChem (11868625)
PubChem (11869366)
PubChem (11869367)
PubChem (11869368)
PubChem (11869369)
PubChem (12120344)
PubChem (12156156)
PubChem (12303135)
PubChem (12303148)
PubChem (12303156)
PubChem (12303159)
PubChem (12303160)
PubChem (117965027)
PubChem (6432564)
PubChem (101624109)
PubChem (6710666)
PubChem (124146240)
PubChem (7059399)
PubChem (124897607)
PubChem (124896959)
PubChem (10861996)
PubChem (132837164)
PubChem (11834483)
PubChem (11888915)
PubChem (11888914)
PubChem (124225449)
PubChem (124429284)
PubChem (124909223)
PubChem (124909224)
PubChem (124909225)
PubChem (138967089)
PubChem (139566851)
PubChem (130459183)
PubChem (131992107)
PubChem (15939944)
PubChem (139568882)
PubChem (142983773)
PubChem (144054483)
PubChem (144209461)
PubChem (144331236)
PubChem (144808354)
PubChem (145053568)
PubChem (145157652)
PubChem (145215073)
PubChem (145230478)
PubChem (146320991)
PubChem (147857230)
PubChem (154993519)
PubChem (171828367)
PubChem (173516975)
PubChem (158603858)
PubChem (162906452)
PubChem (162906453)
PubChem (162906454)
PubChem (162906455)
PubChem (162906456)
PubChem (162906457)
PubChem (163255768)
PubChem (163389210)
PubChem (164665303)
PubChem (166553771)
PubChem (166712004)
PubChem (170116175)
PubChem (171764280)
PubChem (171817101)
PubChem (171817104)
PubChem (174285573)
Sequence modifications
A, C: -25 - 889 (UniProt: P19490)
PDBExternal DatabaseDetails
Asp -6-insertion
Tyr -5-insertion
Lys -4-insertion
Asp -3-insertion
Asp -2-insertion
Asp -1-insertion
Asp 0-insertion
Lys 1-insertion
B, D: -20 - 839 (UniProt: P19491)
PDBExternal DatabaseDetails
Arg 586Gln 607conflict
G, E: 1 - 160 (UniProt: Q5BJU5)
PDBExternal DatabaseDetails
Glu 161-expression tag
Asn 162-expression tag
Leu 163-expression tag
Tyr 164-expression tag
Phe 165-expression tag
Gln 166-expression tag
Ser 167-expression tag
Gly 168-expression tag
Gly 169-expression tag
Ser 170-expression tag
Thr 171-expression tag
Glu 172-expression tag
Thr 173-expression tag
Ser 174-expression tag
Gln 175-expression tag
Val 176-expression tag
Ala 177-expression tag
Pro 178-expression tag
Ala 179-expression tag
Tyr 180-expression tag
Pro 181-expression tag
Tyr 182-expression tag
Asp 183-expression tag
Val 184-expression tag
Pro 185-expression tag
Asp 186-expression tag
Tyr 187-expression tag
Ala 188-expression tag
I, J: 2 - 417 (UniProt: Q8VHW5)
PDBExternal DatabaseDetails
Leu 418-expression tag
Glu 419-expression tag
Val 420-expression tag
Leu 421-expression tag
Phe 422-expression tag
Gln 423-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight528857.1
Non-Polymers*Number of molecules52
Total formula weight38465.1
All*Total formula weight567322.2
*Water molecules are not included.

251422

PDB entries from 2026-04-01

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