7OBY
Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide and stabilizer Fusicoccin-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 253 | 28226.5 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | SSBP4 phosphopeptide | polymer | 11 | 1268.3 | 1 | UniProt (Q9BWG4) | Homo sapiens | Single-stranded DNA-binding protein 4 |
| 3 | C (A) | FUSICOCCIN | non-polymer | 680.8 | 1 | Chemie (FSC) PubChem (46936214) PubChem (24124005) PubChem (44201245) PubChem (52940549) PubChem (57061783) PubChem (58892803) PubChem (143471529) PubChem (89167108) PubChem (89358776) PubChem (270757) PubChem (71308204) PubChem (447573) PubChem (89352860) PubChem (89424149) PubChem (91305733) PubChem (5381214) PubChem (124914704) PubChem (124914702) PubChem (125183286) PubChem (6437071) PubChem (134693211) PubChem (12309993) PubChem (138107212) PubChem (11534864) PubChem (124914703) PubChem (124914705) PubChem (146157920) PubChem (163008024) PubChem (134688043) PubChem (163008025) PubChem (163728719) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29494.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 764.9 | |
| All* | Total formula weight | 30259.7 |
