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7OBS

Crystal structure of 14-3-3 sigma in complex with RIPK2 phosphopeptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer25328226.51UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(B)
Receptor-interacting serine/threonine-protein kinase 2polymer111325.41UniProt (O43353)Homo sapiensCARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
4D, E, F
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5G, H
(A, B)
waterwater18.0420Chemie (HOH)
Sequence modifications
A: 1 - 248 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29552.0
Non-Polymers*Number of molecules4
Total formula weight113.0
All*Total formula weight29665.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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