7OBL
Crystal structure of 14-3-3 sigma in complex with PKR phosphopeptide and stabilizer Fusicoccin-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 14-3-3 protein sigma | polymer | 253 | 28210.5 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B | PKR phosphopeptide | polymer | 11 | 1412.5 | 1 | UniProt (P19525) In PDB | Homo sapiens | Interferon-induced, double-stranded RNA-activated protein kinase,Eukaryotic translation initiation factor 2-alpha kinase 2,eIF-2A protein kinase 2,Interferon-inducible RNA-dependent protein kinase,P1/eIF-2A protein kinase,Protein kinase RNA-activated,PKR,Protein kinase R,Tyrosine-protein kinase EIF2AK2,p68 kinase |
| 3 | A | FUSICOCCIN | non-polymer | 680.8 | 1 | Chemie (FSC) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence modifications
A: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29623.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 729.4 | |
| All* | Total formula weight | 30352.4 |
